{"id":"W4403659584","doi":"10.3389/fimmu.2024.1452106","title":"Contribution of immunoglobulin products in influencing seasonal influenza infection and severity in antibody immune deficiency patients receiving immunoglobulin replacement therapy","year":2024,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Grifols","keywords":"Medicine; Immunology; Vaccination; Antibody; Immune system; Influenza A virus; Hemagglutinin (influenza); Immunoglobulin G; Influenza vaccine; Virology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006213748,0.0002257345,0.0007643265,0.0005501469,0.00007182259,0.0006583516,0.0002460057,0.0003756169,0.001738572],"category_scores_gemma":[0.002557908,0.0000887472,0.00103312,0.0005308768,0.00008296159,0.0002259278,0.0001414057,0.0003721449,0.000142551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002221531,"about_ca_system_score_gemma":0.000374198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009122111,"about_ca_topic_score_gemma":0.001162908,"domain_scores_codex":[0.999652,0.0001425878,0.00009552272,0.00003279153,0.00005968328,0.00001730303],"domain_scores_gemma":[0.9990203,0.0006552887,0.0002132221,0.00001043801,0.00007811379,0.00002263049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003723506,0.0001657223,0.04161319,0.09299117,0.007282793,0.0007532756,0.0003839559,0.0006084145,0.00287457,0.0006403206,0.005194096,0.8437689],"study_design_scores_gemma":[0.00122256,0.007380159,0.4366237,0.1163214,0.05534234,0.008362628,0.001024205,0.001586822,0.005359598,0.002384648,0.3642131,0.0001788321],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01130406,0.9874056,0.0001437001,0.00023421,0.0001096564,0.00002013144,0.0001245765,0.000004396328,0.0006536791],"genre_scores_gemma":[0.111041,0.8865674,0.000735984,0.0004614685,0.0002887077,0.00005658256,0.0002654576,0.000004212692,0.0005793233],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001738572,"threshold_uncertainty_score":0.005816102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0127454896566813,"score_gpt":0.2803085597391085,"score_spread":0.2675630700824271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}