{"id":"W4403664744","doi":"10.1186/s40168-024-01927-5","title":"Metaproteomics reveals diet-induced changes in gut microbiome function according to Crohn’s disease location","year":2024,"lang":"en","type":"article","venue":"Microbiome","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministero della Salute; University of Ottawa; Leona M. and Harry B. Helmsley Charitable Trust","keywords":"Metaproteomics; Biology; Gut microbiome; Microbiome; Crohn's disease; Medical microbiology; Metagenomics; Microbial ecology; Disease; Function (biology); Crohn disease; Microbiology; Immunology; Bioinformatics; Internal medicine; Evolutionary biology; Bacteria; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005026415,0.0003803862,0.0007027321,0.001196476,0.0002827182,0.000697801,0.000184559,0.0003567893,0.001201342],"category_scores_gemma":[0.0005897257,0.0001700791,0.0006562506,0.001213158,0.000163893,0.0003150057,0.0006248846,0.0003951395,0.0002122819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002532983,"about_ca_system_score_gemma":0.0001683953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000611001,"about_ca_topic_score_gemma":0.001136162,"domain_scores_codex":[0.9997041,0.00007519122,0.00002380561,0.00009489463,0.00005191121,0.0000500849],"domain_scores_gemma":[0.9995908,0.00006873421,0.0001710976,0.00004549779,0.00006213724,0.00006182166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003585628,0.0001604378,0.6507586,0.0004632057,0.001743867,0.0002638001,0.0003221494,0.0005497012,0.3172397,0.0001115564,0.0006675972,0.02413372],"study_design_scores_gemma":[0.00001718192,0.0003664724,0.986101,0.00003798604,0.0004668677,0.0005611575,0.0002556958,0.001245292,0.009291107,0.0001789776,0.001460416,0.00001786534],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928605,0.003667893,0.00116961,0.00008675686,0.00001678754,0.00001638112,0.001769274,0.00002895758,0.0003838124],"genre_scores_gemma":[0.9953817,0.0007390532,0.001554457,0.00008590263,0.00001402163,0.00002266612,0.001952685,0.00001431791,0.0002351566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001201342,"threshold_uncertainty_score":0.004018843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01667805197054406,"score_gpt":0.2769257132866417,"score_spread":0.2602476613160976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}