{"id":"W4403671648","doi":"10.1016/j.clcc.2024.10.002","title":"Neoadjuvant Treatment With Regorafenib and Capecitabine Combined With Radiotherapy in Locally Advanced Rectal Cancer: A Multicenter Phase Ib Trial (RECAP)–SAKK 41/16","year":2024,"lang":"en","type":"article","venue":"Clinical Colorectal Cancer","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Bayer Canada; Bayer Corporation","keywords":"Medicine; Capecitabine; Regorafenib; Colorectal cancer; Radiation therapy; Oncology; Internal medicine; Chemo-radiotherapy; Neoadjuvant therapy; Phases of clinical research; Chemotherapy; Cancer; Breast cancer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001929848,0.001815271,0.003000126,0.0004568739,0.0004566901,0.001144451,0.0008372224,0.001212215,0.005442629],"category_scores_gemma":[0.001008904,0.0006933464,0.002782151,0.0005966776,0.001247544,0.001083651,0.0005892262,0.004505128,0.001414528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00138888,"about_ca_system_score_gemma":0.002007109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001674847,"about_ca_topic_score_gemma":0.005782492,"domain_scores_codex":[0.9992398,0.0003932624,0.00004603826,0.0001368002,0.00004428119,0.0001398321],"domain_scores_gemma":[0.9992415,0.000103499,0.0001707896,0.00009187883,0.00003372602,0.0003585916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8707416,0.0179632,0.002519425,0.001482211,0.00220769,0.0001097402,0.0001772086,0.003151915,0.01700734,0.000308346,0.005467254,0.07886404],"study_design_scores_gemma":[0.6809763,0.3019682,0.007499648,0.0001262916,0.001256844,0.0002274245,0.00008004126,0.0006177354,0.002128208,0.0002121988,0.004859109,0.00004816757],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9801005,0.009234883,0.0005333134,0.001977496,0.0005671198,0.001785111,0.002128136,0.0001657169,0.003507646],"genre_scores_gemma":[0.9654534,0.009620957,0.002987044,0.002543076,0.0006112592,0.00393941,0.006710195,0.000137712,0.0079969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005442629,"threshold_uncertainty_score":0.01820737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0323816881087118,"score_gpt":0.3890605521613176,"score_spread":0.3566788640526058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}