{"id":"W4403679882","doi":"10.1016/j.bbadis.2024.167548","title":"Thioredoxin-1 protein interactions in neuronal survival and neurodegeneration","year":2024,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Institute of Neurosciences, Mental Health and Addiction; Natural Sciences and Engineering Research Council of Canada","keywords":"Neurodegeneration; Thioredoxin; Neuroscience; Biology; Medicine; Oxidative stress; Disease; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002188664,0.0003535835,0.0002652558,0.0003585597,0.0004016815,0.0004242447,0.0002369925,0.0004375323,0.00103347],"category_scores_gemma":[0.00008426166,0.0001157384,0.0003012395,0.0002932232,0.0001925621,0.0003360895,0.000337275,0.0004882365,0.0005318416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005203364,"about_ca_system_score_gemma":0.0002319495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005715716,"about_ca_topic_score_gemma":0.001077456,"domain_scores_codex":[0.9998854,0.00001984783,0.000006354163,0.0000317064,0.00003098735,0.00002570137],"domain_scores_gemma":[0.9999553,0.000003302813,0.00001823474,0.000003022631,0.000009579015,0.00001063769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004280944,0.000106555,0.004833012,0.0005136035,0.0001013563,0.000628622,0.0001559287,0.0004220704,0.9619609,0.002101535,0.001296287,0.02745206],"study_design_scores_gemma":[0.00004721931,0.0008095193,0.1243298,0.0001627486,0.0002331547,0.003435619,0.0004958516,0.003711086,0.7865531,0.00401605,0.07615535,0.00005045738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8742855,0.1144162,0.004068246,0.001133747,0.0001625309,0.00003027246,0.0004443575,0.0001565022,0.005302748],"genre_scores_gemma":[0.9593116,0.02940105,0.002155267,0.0002440312,0.00005692829,0.00002230597,0.0007229391,0.00001439223,0.008071555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00103347,"threshold_uncertainty_score":0.003775299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01031663554561192,"score_gpt":0.273354340395779,"score_spread":0.2630377048501671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}