{"id":"W4403694937","doi":"10.1016/j.mtcomm.2024.110775","title":"Designing of amiloride loaded citrate functionalized amorphous silica nanoparticles to investigate its genotoxic and cytotoxic potential","year":2024,"lang":"en","type":"article","venue":"Materials Today Communications","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Innovation Cluster (Canada)","funders":"University of Delhi; Council of Scientific and Industrial Research, India","keywords":"Materials science; Amorphous solid; Nanoparticle; Cytotoxic T cell; Amorphous silica; Nanotechnology; Amiloride; Chemical engineering; Cytotoxicity; Sodium citrate; Organic chemistry; Sodium; Biochemistry; Metallurgy; In vitro; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005458352,0.0001596366,0.0003754285,0.0001498587,0.0001817906,0.0001197191,0.0002382506,0.00005819646,0.0005003372],"category_scores_gemma":[0.0001882023,0.0001302036,0.00005943552,0.0002259056,0.0001789297,0.0001045657,0.0002500887,0.00008979564,0.0001164678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002730816,"about_ca_system_score_gemma":0.0000938423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008477928,"about_ca_topic_score_gemma":0.000007194582,"domain_scores_codex":[0.9986024,0.0002841357,0.0005151677,0.0002275325,0.0001797169,0.0001910315],"domain_scores_gemma":[0.9987893,0.000152428,0.0000754813,0.0007363381,0.0001005211,0.0001458914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001625823,0.00004492036,0.00001594702,0.000206569,0.00008816081,0.000003620502,0.000378905,0.00001235653,0.9969368,0.001566575,0.0001748407,0.000408713],"study_design_scores_gemma":[0.000238871,0.000143525,0.001501771,0.0003281874,0.000156244,0.00004814524,0.00006947882,0.000212951,0.9927444,0.0006993128,0.003722627,0.0001345031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910868,0.004641689,0.0002167245,0.00279321,0.0001644134,0.0005577861,0.00006700064,0.0001293123,0.0003430973],"genre_scores_gemma":[0.9908542,0.0003972862,0.007613444,0.0003251523,0.00006286939,0.0001484278,0.00003765939,0.00003404345,0.0005268864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007396719,"threshold_uncertainty_score":0.5478341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0771366697077749,"score_gpt":0.2921008622174792,"score_spread":0.2149641925097043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}