{"id":"W4403721083","doi":"10.14309/01.ajg.0001036892.89042.29","title":"S1881 Long-Term Efficacy and Safety of Open-Label Seladelpar Treatment in Patients With Primary Biliary Cholangitis: Interim Results for 2 Years From the ASSURE Study","year":2024,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Gallbladder and Bile Duct Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Liver Centre; University of Toronto","funders":"","keywords":"Medicine; Interim; Interim analysis; Open label; Term (time); Internal medicine; Surgery; Adverse effect; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003902411,0.0007643535,0.002171193,0.0002635296,0.0003356533,0.001188499,0.0005147397,0.001084318,0.008581492],"category_scores_gemma":[0.002270036,0.0003407964,0.002301879,0.0003415309,0.000515073,0.0008307018,0.0004084116,0.002650696,0.001912988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003723845,"about_ca_system_score_gemma":0.0007185102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002249234,"about_ca_topic_score_gemma":0.0006302363,"domain_scores_codex":[0.9988006,0.0006404676,0.00008272548,0.0001175075,0.0001856523,0.0001729867],"domain_scores_gemma":[0.9977307,0.0005351183,0.00073213,0.0003178316,0.0002327252,0.0004514525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.768647,0.02119776,0.01695671,0.001818657,0.003662976,0.0003421988,0.000318074,0.001767691,0.02163082,0.0007025368,0.01789885,0.1450568],"study_design_scores_gemma":[0.3692398,0.5196948,0.07537813,0.000186852,0.002555332,0.000859235,0.0001782372,0.001513416,0.008791969,0.0006781556,0.02083714,0.00008694877],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9654011,0.007602194,0.002095479,0.001423634,0.0004090204,0.002019762,0.01277702,0.0004171419,0.007854637],"genre_scores_gemma":[0.973543,0.002009423,0.002687644,0.001769911,0.0005573751,0.0019344,0.01250472,0.00007586943,0.004917572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008581492,"threshold_uncertainty_score":0.02870792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01858053969560604,"score_gpt":0.3001251366889428,"score_spread":0.2815445969933367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}