{"id":"W4403721970","doi":"10.14309/01.ajg.0001034956.49581.14","title":"S1397 Long-Term Efficacy and Safety of Intravenous (IV) Tulisokibart in Patients With Crohn’s Disease (CD): Results from the Open-Label Extension Period of the Phase 2 APOLLO-CD Study","year":2024,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Apollo; Crohn's disease; Term (time); Period (music); Open label; Disease; Surgery; Internal medicine; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003515714,0.0004078168,0.001112654,0.000329379,0.0003450451,0.0007439372,0.0002844415,0.0008468368,0.007795846],"category_scores_gemma":[0.003066385,0.0002044533,0.0016276,0.0004981247,0.000355339,0.0005732685,0.0002607683,0.001146263,0.001401478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000319329,"about_ca_system_score_gemma":0.0009437996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002324458,"about_ca_topic_score_gemma":0.0006480538,"domain_scores_codex":[0.9986709,0.0006893884,0.0001898349,0.0001097756,0.0002493473,0.0000906998],"domain_scores_gemma":[0.9966017,0.001427238,0.0009465397,0.0001695949,0.0005476857,0.0003072414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4635749,0.01074628,0.06188966,0.009029441,0.004257358,0.0005203829,0.0004039234,0.00101119,0.02343624,0.0007232396,0.02614034,0.398267],"study_design_scores_gemma":[0.2467904,0.436292,0.2222224,0.003713292,0.006092828,0.002010728,0.0006295831,0.002475169,0.01136404,0.001610711,0.06661719,0.0001817465],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9294956,0.03539786,0.001645615,0.002377735,0.0007118147,0.002646587,0.01319041,0.0001293446,0.01440492],"genre_scores_gemma":[0.9601073,0.01314301,0.002998682,0.003347202,0.0009872724,0.002386257,0.01266779,0.00005644706,0.004306066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007795846,"threshold_uncertainty_score":0.02607971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008147443173243438,"score_gpt":0.2608333313964806,"score_spread":0.2526858882232371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}