{"id":"W4403722795","doi":"10.14309/01.ajg.0001035156.82149.4f","title":"S1447 Histologic and Combined Histologic and Endoscopic Outcomes After Guselkumab Maintenance Therapy in Patients With Moderately to Severely Active Ulcerative Colitis: Week 44 Results From the Phase 3 QUASAR Maintenance Study","year":2024,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Ulcerative colitis; Maintenance therapy; Surgery; Rescue therapy; Internal medicine; Dermatology; Gastroenterology; Chemotherapy; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002015026,0.0004621599,0.001511742,0.000217048,0.0002480553,0.0005417895,0.0004534312,0.0006501014,0.001834725],"category_scores_gemma":[0.0007527898,0.000240277,0.001315547,0.0002848073,0.0003088971,0.0005181694,0.000278885,0.00113161,0.0004025497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003642222,"about_ca_system_score_gemma":0.0005746079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003502145,"about_ca_topic_score_gemma":0.00078672,"domain_scores_codex":[0.9993628,0.0003298015,0.00005252878,0.00007197342,0.00009869794,0.00008423152],"domain_scores_gemma":[0.9992446,0.0001135963,0.0002740232,0.00006664825,0.00006935928,0.0002319522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7410402,0.01622184,0.09777192,0.0006606566,0.002626098,0.0002313592,0.0002221559,0.0009526805,0.03422524,0.00007575592,0.002392687,0.1035794],"study_design_scores_gemma":[0.1771785,0.5045444,0.3085271,0.00009149055,0.001694284,0.0003641231,0.00009622589,0.001116494,0.003752682,0.0001215781,0.002464337,0.00004891396],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976081,0.001226168,0.0001222534,0.0001068205,0.00001880831,0.0001798568,0.0003230496,0.00001678433,0.0003982968],"genre_scores_gemma":[0.9969816,0.0005104755,0.0003333069,0.0002491249,0.00007217176,0.0002656341,0.0009510373,0.000005815099,0.0006309273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002015026,"threshold_uncertainty_score":0.0106566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008360601457940249,"score_gpt":0.2429993956921504,"score_spread":0.2346387942342102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}