{"id":"W4403723115","doi":"10.14309/01.ajg.0001035184.00247.3f","title":"S1454 Long-Term Efficacy and Safety of Intravenous (IV) Tulisokibart in Patients With Ulcerative Colitis (UC): Results From the Open-Label Extension (OLE) Period of the Phase 2 ARTEMIS-UC Study","year":2024,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Calgary","funders":"","keywords":"Medicine; Ulcerative colitis; Open label; Internal medicine; Term (time); Colitis; Gastroenterology; Adverse effect; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001212194,0.0005410147,0.001420871,0.0002612334,0.0002564557,0.0008475949,0.0003873722,0.001063129,0.005436562],"category_scores_gemma":[0.001428414,0.0002723363,0.001661134,0.0003589853,0.000368335,0.0005498527,0.0002814724,0.001556191,0.001122495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003620588,"about_ca_system_score_gemma":0.0007972216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003803288,"about_ca_topic_score_gemma":0.0008497111,"domain_scores_codex":[0.9995013,0.0002738355,0.00006099453,0.00005489019,0.00005704977,0.00005182457],"domain_scores_gemma":[0.9987539,0.0003215275,0.000395804,0.00008455837,0.0001512486,0.0002930963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7611462,0.01218692,0.02098203,0.001922892,0.003458724,0.0002606997,0.0002054093,0.0007553917,0.0202271,0.000218448,0.008360703,0.1702754],"study_design_scores_gemma":[0.4697286,0.407575,0.09870901,0.0004370102,0.003824624,0.0005731962,0.0001769112,0.001687352,0.004864338,0.0003833463,0.01195508,0.00008552747],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978957,0.01316167,0.0004222534,0.0008275856,0.0003209389,0.0006043649,0.003053821,0.00007764263,0.002574748],"genre_scores_gemma":[0.9852754,0.004166622,0.001006887,0.00137256,0.0005127305,0.0005632065,0.00496345,0.00002170268,0.002117613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005436562,"threshold_uncertainty_score":0.01818717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008283993960475553,"score_gpt":0.2628276205595454,"score_spread":0.2545436265990699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}