{"id":"W4403723408","doi":"10.14309/01.ajg.0001035084.95280.e1","title":"S1429 Efficacy of Guselkumab in Moderately to Severely Active Crohn’s Disease According to Induction Clinical Response Status: Week 48 Results from the GALAXI 2 & 3 Phase 3 Trials","year":2024,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Crohn's disease; Internal medicine; Disease; Clinical trial; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003850479,0.0008960838,0.002339013,0.0003299306,0.0003340298,0.0009601264,0.0005578631,0.001446278,0.008462935],"category_scores_gemma":[0.002663819,0.0003214071,0.003828723,0.0004510642,0.0005702113,0.0007811908,0.0004119427,0.002179618,0.001466148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005103477,"about_ca_system_score_gemma":0.001019088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003654681,"about_ca_topic_score_gemma":0.001386315,"domain_scores_codex":[0.9984605,0.0009921713,0.0001531651,0.0001520323,0.0001309169,0.0001111408],"domain_scores_gemma":[0.9983373,0.0006630888,0.0004692145,0.0001360695,0.0001442897,0.0002499886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8967801,0.002353566,0.003341075,0.004309117,0.006071654,0.00009503009,0.0001217726,0.0006838246,0.01008611,0.0003340725,0.005524772,0.07029895],"study_design_scores_gemma":[0.8380944,0.1143299,0.02465228,0.0007794988,0.006869036,0.0002118198,0.00008545817,0.0008564186,0.002971952,0.001170119,0.009915762,0.00006331457],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9206406,0.04074914,0.002689144,0.003301178,0.0007798586,0.008547447,0.009549129,0.0003370173,0.01340634],"genre_scores_gemma":[0.9700091,0.007540387,0.002489904,0.003002667,0.0005188884,0.005614062,0.006424855,0.00006795166,0.004332119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008462935,"threshold_uncertainty_score":0.02831131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05284597707410257,"score_gpt":0.3765929902731573,"score_spread":0.3237470131990547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}