{"id":"W4403724305","doi":"10.14309/01.ajg.0001034328.68326.43","title":"S1240 The Efficacy of Maintenance Treatment with Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: Phase 3 QUASAR Maintenance Study Results at Week 44 by Biologic/Janus Kinase History","year":2024,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; McGill University Health Centre","funders":"","keywords":"Medicine; Ulcerative colitis; Maintenance therapy; Internal medicine; Dermatology; Surgery; Chemotherapy; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00124823,0.0004605413,0.001377666,0.000239269,0.0002114105,0.0005055231,0.000448024,0.0005457253,0.003658828],"category_scores_gemma":[0.000609341,0.0002421026,0.001104552,0.0002723181,0.0003672593,0.0004170235,0.0001985174,0.001393067,0.0005829436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003204751,"about_ca_system_score_gemma":0.0005821874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003112621,"about_ca_topic_score_gemma":0.0008459162,"domain_scores_codex":[0.9996946,0.0001535405,0.00002642278,0.00003298211,0.00005218426,0.00004029884],"domain_scores_gemma":[0.9994612,0.0001112128,0.0001949064,0.00003585307,0.00004893286,0.0001478441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7352545,0.0142949,0.01525852,0.001607899,0.002408351,0.0001698458,0.0001474461,0.0007612209,0.06316655,0.0001279659,0.003659365,0.1631434],"study_design_scores_gemma":[0.3624559,0.5615691,0.06288436,0.0001084842,0.00149483,0.000370479,0.00004645844,0.0009161742,0.006458395,0.0001079206,0.003553232,0.0000346311],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918269,0.004886601,0.0002572612,0.0003137174,0.00006011902,0.0005718509,0.0008466623,0.00006612664,0.001170764],"genre_scores_gemma":[0.9939382,0.001729354,0.0006474664,0.000492376,0.0001698284,0.00046037,0.001391962,0.00001311422,0.001157367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003658828,"threshold_uncertainty_score":0.01223999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008954632330051794,"score_gpt":0.2397395134681765,"score_spread":0.2307848811381247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}