{"id":"W4403724982","doi":"10.14309/01.ajg.0001033576.85427.3d","title":"S1052 Efficacy and Safety of Subcutaneous Guselkumab Induction Therapy in Patients With Moderately to Severely Active Crohn’s Disease: Results Through Week 48 From the Phase 3 GRAVITI Study","year":2024,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Crohn's disease; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009682526,0.0004504362,0.001216386,0.0001922209,0.0002592818,0.0005433842,0.0003124502,0.0005773241,0.002570721],"category_scores_gemma":[0.000637938,0.0001903207,0.001053226,0.0002675542,0.0003986087,0.0003672043,0.000246937,0.001384783,0.0004898863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005009238,"about_ca_system_score_gemma":0.0006735669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004683087,"about_ca_topic_score_gemma":0.001286285,"domain_scores_codex":[0.9996605,0.0001729467,0.00002547793,0.00003949382,0.00004509351,0.00005657671],"domain_scores_gemma":[0.9995232,0.00008816402,0.0001359087,0.00004326327,0.00003487585,0.000174513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7372171,0.01600656,0.01742617,0.00073946,0.001375776,0.0002284921,0.0002760784,0.001380457,0.0534256,0.0001767514,0.004056633,0.1676908],"study_design_scores_gemma":[0.2817763,0.6097248,0.09571331,0.00008086611,0.001054178,0.0004309054,0.00008513977,0.001186924,0.005553706,0.0001932952,0.00415791,0.00004276216],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961901,0.001674395,0.000186028,0.0002238742,0.00002784269,0.0002609424,0.000441015,0.00004701285,0.0009488769],"genre_scores_gemma":[0.9966523,0.0005910278,0.000457805,0.0002858872,0.00005905407,0.0002703088,0.0009769301,0.00001087914,0.0006957006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002570721,"threshold_uncertainty_score":0.008599937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009468867846487596,"score_gpt":0.2587499891650591,"score_spread":0.2492811213185716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}