{"id":"W4403726637","doi":"10.14309/01.ajg.0001033568.21496.22","title":"S1050 Efficacy and Safety of Upadacitinib Maintenance Treatment in Patients With Moderately to Severely Active Crohn’s Disease: Two Year Results From the U-ENDURE Long-Term Extension Study","year":2024,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Term (time); Crohn's disease; Extension (predicate logic); Disease; Crohn disease; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002630607,0.0003791029,0.001189203,0.0002328861,0.0003186025,0.0007638758,0.0003385221,0.0006570316,0.001393965],"category_scores_gemma":[0.002099263,0.0002011549,0.001417957,0.0003461996,0.0002422349,0.0005219952,0.0004287429,0.0008997571,0.0004107996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003038534,"about_ca_system_score_gemma":0.0004007236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005551486,"about_ca_topic_score_gemma":0.001530932,"domain_scores_codex":[0.999221,0.0004088043,0.00008506504,0.00009043528,0.0001083139,0.00008643001],"domain_scores_gemma":[0.998163,0.0003844712,0.00065586,0.0001894592,0.000222851,0.0003843458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5617834,0.006507782,0.2493452,0.001234002,0.006457406,0.0003363419,0.0003279311,0.001085949,0.01123482,0.0001497966,0.004872509,0.1566649],"study_design_scores_gemma":[0.07090802,0.1408983,0.7716973,0.0002802295,0.005823085,0.0006533024,0.0001458566,0.001574803,0.002705842,0.0001779677,0.005054819,0.00008039102],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994011,0.003358601,0.0001593514,0.000158228,0.00003187611,0.0001699149,0.001247268,0.00001936812,0.0008443477],"genre_scores_gemma":[0.9953821,0.0006549596,0.0003620268,0.0002624368,0.00006762258,0.0001517736,0.002600403,0.000004686753,0.0005138847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002630607,"threshold_uncertainty_score":0.01391214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007007993530837312,"score_gpt":0.2483742325351258,"score_spread":0.2413662390042885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}