{"id":"W4403749078","doi":"10.1002/ueg2.12686","title":"Distinct trajectories of symptomatic response in ulcerative colitis during filgotinib therapy: A post hoc analysis from the SELECTION study","year":2024,"lang":"en","type":"article","venue":"United European Gastroenterology Journal","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Western University","funders":"Galápagos; Gilead Sciences","keywords":"Medicine; Ulcerative colitis; Post-hoc analysis; Internal medicine; Post hoc; Clinical endpoint; Disease; Randomized controlled trial; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01078427,0.0008800141,0.001303401,0.0005111514,0.000545813,0.000883851,0.0008156073,0.0005454074,0.002389272],"category_scores_gemma":[0.01102266,0.0002537595,0.003950668,0.0005015456,0.0005382716,0.0006109151,0.001013307,0.001455089,0.00019174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008232892,"about_ca_system_score_gemma":0.001805101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003346821,"about_ca_topic_score_gemma":0.003375069,"domain_scores_codex":[0.9948078,0.003642951,0.0001563867,0.0005941426,0.0003108262,0.0004878999],"domain_scores_gemma":[0.9893133,0.00658157,0.001334765,0.001743375,0.0004763928,0.0005506632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1111151,0.002785058,0.8226476,0.0002666306,0.01035313,0.0006160812,0.001040763,0.01310932,0.003782859,0.0004904895,0.003555498,0.03023749],"study_design_scores_gemma":[0.002322322,0.03558839,0.8876584,0.00004423668,0.004211907,0.0003680231,0.00103631,0.06393939,0.002002695,0.0007331686,0.002014849,0.00008036382],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983272,0.00006344173,0.0009043551,0.00004500164,0.00001368357,0.0001009637,0.0004076774,0.0000149776,0.0001227501],"genre_scores_gemma":[0.9971333,0.00002645773,0.0007212167,0.00004054011,0.00001293031,0.0002519995,0.001493292,0.00001386728,0.0003063961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01078427,"threshold_uncertainty_score":0.05703336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006983404439145317,"score_gpt":0.2344145741370976,"score_spread":0.2274311696979523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}