{"id":"W4403753361","doi":"10.1056/nejmoa2409415","title":"Atrasentan in Patients with IgA Nephropathy","year":2024,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Novartis","keywords":"Nephropathy; Medicine; Endocrinology; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008818901,0.0002698551,0.001032883,0.0002005296,0.0002601547,0.0002479269,0.0002440813,0.0003066597,0.001685042],"category_scores_gemma":[0.0008604066,0.0001090165,0.0006092878,0.0003280343,0.0001475343,0.0001606826,0.0002139145,0.0006927761,0.0002322342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000261023,"about_ca_system_score_gemma":0.0005243247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004696686,"about_ca_topic_score_gemma":0.001164568,"domain_scores_codex":[0.9996964,0.0001271635,0.00003812366,0.00004435435,0.00005408913,0.00003988511],"domain_scores_gemma":[0.9995421,0.0001135594,0.0001653288,0.00001869938,0.00003461223,0.0001256808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2000114,0.006324682,0.2285335,0.00464431,0.003114008,0.001826178,0.0004434401,0.001588166,0.02587667,0.0005125147,0.006711787,0.5204133],"study_design_scores_gemma":[0.08850739,0.2253097,0.6304227,0.001194516,0.005026375,0.008062551,0.0004144735,0.003499403,0.007943966,0.001470409,0.02806274,0.00008595482],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9649424,0.03087216,0.0003159943,0.0006270149,0.0001298687,0.0002059209,0.0001744113,0.00003905808,0.002693206],"genre_scores_gemma":[0.9922308,0.005732952,0.0005045657,0.0006510022,0.0001382979,0.00008902462,0.0002223419,0.000003002953,0.0004280246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001685042,"threshold_uncertainty_score":0.00563705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00664500828498019,"score_gpt":0.2474850847952177,"score_spread":0.2408400765102375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}