{"id":"W4403762784","doi":"10.1152/ajpheart.00639.2024","title":"Human sympathetic neuronal discharge and recruitment patterns regulate neuropeptide Y bioavailability","year":2024,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Brock University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Natural Sciences and Engineering Research Council of Canada; Government of Canada; National Institutes of Health; Brock University; Canada Research Chairs; American Heart Association","keywords":"Neuropeptide Y receptor; Microneurography; Norepinephrine; Mean arterial pressure; Internal medicine; Endocrinology; Medicine; Sympatholytic; Dexmedetomidine; Sympathetic nervous system; Blood pressure; Agonist; Neurotransmitter; Baroreflex; Anesthesia; Heart rate; Neuropeptide; Receptor; Dopamine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001797877,0.00009104882,0.0002875518,0.0001385233,0.0001098886,0.0003192538,0.00005770759,0.0001310534,0.0008907032],"category_scores_gemma":[0.0005353977,0.00006456413,0.00007496852,0.0001127052,0.0001507392,0.0001199366,0.0001319979,0.0001937977,0.0001696359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001054707,"about_ca_system_score_gemma":0.00009366146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003287124,"about_ca_topic_score_gemma":0.0005960458,"domain_scores_codex":[0.9999117,0.00002698848,0.000006207996,0.00002462373,0.00001976965,0.00001078262],"domain_scores_gemma":[0.999831,0.00005503285,0.00004733968,0.00001449109,0.00002530556,0.00002686369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006449368,0.0002078579,0.2357567,0.0001489375,0.0001148926,0.0005671409,0.0004934704,0.000342219,0.6944809,0.0002162658,0.0003608969,0.06086138],"study_design_scores_gemma":[0.00003003893,0.0009828173,0.9680778,0.00001723304,0.00005148654,0.0009742854,0.0002217004,0.0009266362,0.02769662,0.0001610452,0.0008483414,0.0000120132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977825,0.0006075325,0.0009268395,0.00001920888,0.000006802841,0.000008118881,0.00007072664,0.000005043764,0.0005731498],"genre_scores_gemma":[0.9987225,0.0003149839,0.0004185286,0.00003111735,0.00000742422,0.0000140202,0.0001081911,0.00000274523,0.0003805509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008907032,"threshold_uncertainty_score":0.002979696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03719569687922928,"score_gpt":0.284465320629107,"score_spread":0.2472696237498777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}