{"id":"W4403764293","doi":"10.3390/microorganisms12112148","title":"How Gut Microbiome Perturbation Caused by Antibiotic Pre-Treatments Affected the Conjugative Transfer of Antimicrobial Resistance Genes","year":2024,"lang":"en","type":"article","venue":"Microorganisms","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"Public Health Agency; Public Health Agency of Canada; Government of Canada; Canadian Food Inspection Agency","keywords":"Antibiotic resistance; Microbiome; Antibiotics; Antimicrobial; Microbiology; Biology; Gene; Gene transfer; Horizontal gene transfer; Genetics; Phylogenetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002099481,0.0002907992,0.0003367784,0.0002010511,0.0001540443,0.0005271389,0.0001317699,0.000458088,0.001579653],"category_scores_gemma":[0.0002510024,0.0001645287,0.0003157929,0.0001471343,0.0003464897,0.0003503193,0.000295039,0.0008308938,0.0002951433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002352919,"about_ca_system_score_gemma":0.0003474387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006526688,"about_ca_topic_score_gemma":0.0009764647,"domain_scores_codex":[0.9996982,0.00006088756,0.00001693684,0.00007847438,0.00005419787,0.00009138694],"domain_scores_gemma":[0.999891,0.00001622168,0.00003227224,0.00001046721,0.00001482686,0.00003521124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009366213,0.0001562629,0.002204931,0.0001474102,0.00002850779,0.0001257174,0.00007444383,0.0002093128,0.9896662,0.0001915587,0.0002089532,0.006049929],"study_design_scores_gemma":[0.00007763765,0.003350668,0.08512761,0.00009434504,0.0001589097,0.0004938086,0.00055148,0.003465862,0.8948474,0.0008463816,0.01093295,0.00005282519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888631,0.002925965,0.004149939,0.0003961322,0.0001829876,0.00007087914,0.0009425188,0.0001125861,0.002355827],"genre_scores_gemma":[0.9922806,0.001870389,0.002286892,0.0003282181,0.00002008167,0.0001012867,0.0004560254,0.0000330514,0.002623588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001579653,"threshold_uncertainty_score":0.005284429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005505379060970365,"score_gpt":0.2250183061670067,"score_spread":0.2195129271060363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}