{"id":"W4403764293","doi":"10.3390/microorganisms12112148","title":"How Gut Microbiome Perturbation Caused by Antibiotic Pre-Treatments Affected the Conjugative Transfer of Antimicrobial Resistance Genes","year":2024,"lang":"en","type":"article","venue":"Microorganisms","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"Public Health Agency; Public Health Agency of Canada; Government of Canada; Canadian Food Inspection Agency","keywords":"Antibiotic resistance; Microbiome; Antibiotics; Antimicrobial; Microbiology; Biology; Gene; Gene transfer; Horizontal gene transfer; Genetics; Phylogenetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001156768,0.0002741128,0.0002407403,0.00005703573,0.0001535212,0.0001135905,0.0002371495,0.0002188856,0.00001989786],"category_scores_gemma":[0.00001215343,0.0002028593,0.0001292064,0.0002313257,0.0002239271,0.00001114329,0.00004635081,0.0001165187,0.00001146738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005071547,"about_ca_system_score_gemma":0.0001485593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002583481,"about_ca_topic_score_gemma":0.00008459045,"domain_scores_codex":[0.9987196,0.0001245064,0.0002430921,0.0004979084,0.00008668865,0.0003282262],"domain_scores_gemma":[0.9994246,0.00002016695,0.0000557842,0.0003449544,0.00009982078,0.00005463566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005053158,0.00009755776,0.00007928359,0.0002215721,0.0002067807,0.000003967268,0.0005377685,6.947299e-7,0.9793912,0.000033015,0.01920303,0.0001746611],"study_design_scores_gemma":[0.0005825352,0.0001603307,0.00182792,0.000109523,0.0001022477,0.00001778593,0.00008518956,0.000002326838,0.9774831,0.000008073223,0.01940378,0.0002171948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875618,0.007098849,0.001758794,0.001892192,0.0002863076,0.0006111866,0.0006976145,0.00003897989,0.00005426489],"genre_scores_gemma":[0.9890316,0.000637472,0.0002230438,0.0003230503,0.0000990539,0.000005640681,0.0007646599,0.00005694479,0.008858608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008804343,"threshold_uncertainty_score":0.8272362,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005505379060970365,"score_gpt":0.2250183061670067,"score_spread":0.2195129271060363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}