{"id":"W4403807854","doi":"10.1093/eurheartj/ehae666.2279","title":"Extracranial systemic embolic events in patients with atrial fibrillation: an individual patient-level meta-analysis of 71 683 patients randomized to NOAC vs warfarin from the COMBINE-AF study","year":2024,"lang":"en","type":"article","venue":"European Heart Journal","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute","funders":"","keywords":"Medicine; Atrial fibrillation; Warfarin; Internal medicine; Cardiology; Meta-analysis; Randomized controlled trial; Embolic stroke; Ischemic stroke","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01012006,0.002147046,0.01064622,0.001844747,0.0004563734,0.002756035,0.00128875,0.001705302,0.003033512],"category_scores_gemma":[0.0150089,0.001135027,0.03703006,0.002491257,0.0004906827,0.001043472,0.0009552535,0.001957664,0.0003648256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008570379,"about_ca_system_score_gemma":0.0006486449,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003005129,"about_ca_topic_score_gemma":0.00506361,"domain_scores_codex":[0.9915947,0.005269761,0.001289258,0.001076278,0.0005472415,0.0002226628],"domain_scores_gemma":[0.9904918,0.006636248,0.00143904,0.0007998272,0.0004429945,0.0001900604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.01215035,0.00003550308,0.008829491,0.01201564,0.9620615,0.00008068368,0.00002685623,0.0009183,0.0002848847,0.00007168399,0.0004133974,0.003111613],"study_design_scores_gemma":[0.002871529,0.000455477,0.008712677,0.0006289175,0.9856732,0.00006218826,0.00001922674,0.0005132626,0.0001146953,0.0002525574,0.000675886,0.00002053244],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2012681,0.7850225,0.004430965,0.0009284902,0.0007532029,0.0004386822,0.005041297,0.000224022,0.001892769],"genre_scores_gemma":[0.9547709,0.03923656,0.001809855,0.0008327566,0.0003085378,0.000377388,0.002131932,0.00005754323,0.0004745723],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01064622,"threshold_uncertainty_score":0.05352056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1256592983982614,"score_gpt":0.3414565279029066,"score_spread":0.2157972295046452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}