{"id":"W4403811510","doi":"10.1089/aid.2024.0062","title":"Central Memory CD4 T Cells from Persons with HIV Accumulate DNA Content Defects During Proliferative Response","year":2024,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institutes of Health; Consejo Nacional de Ciencia y Tecnología","keywords":"Human immunodeficiency virus (HIV); DNA; Biology; Virology; Lentivirus; Immunology; Cancer research; Genetics; Viral disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008473191,0.0002011537,0.0002364348,0.0003490085,0.0002481168,0.0003141371,0.0001449362,0.0002432287,0.002367046],"category_scores_gemma":[0.0002854722,0.0001256951,0.0001145349,0.0001675805,0.0001606754,0.0001753348,0.0001837362,0.0003362946,0.0002878425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001024819,"about_ca_system_score_gemma":0.00007535082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005249027,"about_ca_topic_score_gemma":0.0005407907,"domain_scores_codex":[0.9999257,0.000009581363,0.000006726278,0.00002015201,0.00001671225,0.0000211857],"domain_scores_gemma":[0.999868,0.00002692391,0.00003704496,0.00001161639,0.00002716589,0.00002921941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002564213,0.0002391188,0.1655485,0.0002117974,0.00004800306,0.002923322,0.0009631914,0.0001014431,0.7913871,0.00009061,0.0004137904,0.0355089],"study_design_scores_gemma":[0.00006995905,0.002797075,0.8164082,0.00004850731,0.0001040923,0.01172179,0.001509785,0.0004211827,0.164724,0.0002082786,0.00197344,0.00001371747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992207,0.0002765327,0.0000996957,0.00001367007,0.000003318079,0.000004892321,0.00005542396,0.000006926558,0.0003187446],"genre_scores_gemma":[0.999236,0.0001068328,0.00009099525,0.00002311711,0.000006094308,0.000007848729,0.0001009686,0.000002179048,0.0004259569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002367046,"threshold_uncertainty_score":0.007918596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07308128316392756,"score_gpt":0.3317217050013714,"score_spread":0.2586404218374438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}