{"id":"W4403824763","doi":"10.1016/j.cllc.2024.10.009","title":"A Poor Prognostic ALK Phenotype: A Review of Molecular Markers of Poor Prognosis in ALK Rearranged Nonsmall Cell Lung Cancer","year":2024,"lang":"en","type":"review","venue":"Clinical Lung Cancer","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital du Sacré-Cœur de Montréal; Princess Margaret Cancer Centre; University Health Network; Juravinski Cancer Centre","funders":"","keywords":"Medicine; Lung cancer; Phenotype; Crizotinib; Oncology; Pathology; Internal medicine; Cancer research; Gene; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001189063,0.001107826,0.003239476,0.003198025,0.000222315,0.0013364,0.001314627,0.001224793,0.002325191],"category_scores_gemma":[0.001982337,0.0004605001,0.001276517,0.003605312,0.0004651417,0.001528345,0.0008281656,0.001991761,0.000876953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006737798,"about_ca_system_score_gemma":0.001600085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001767258,"about_ca_topic_score_gemma":0.00411378,"domain_scores_codex":[0.9996079,0.00006796738,0.0001074926,0.00007627391,0.0001133413,0.00002708307],"domain_scores_gemma":[0.998798,0.0007145442,0.0001886738,0.0000173915,0.0002226772,0.00005870873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001876554,0.00005714322,0.0004816043,0.05672364,0.0005005476,0.0001554047,0.00004832327,0.0003342504,0.0008241271,0.001029642,0.03414892,0.9055088],"study_design_scores_gemma":[0.0002170765,0.000428195,0.005484801,0.04878735,0.003797509,0.002539929,0.0001862912,0.0003655605,0.0005333356,0.002208949,0.9353278,0.0001231723],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003768196,0.9995878,0.0000426848,0.0001169116,0.00009166986,0.000002805908,0.00001978709,0.000002567568,0.00009793998],"genre_scores_gemma":[0.0002657112,0.9991873,0.0001077009,0.0002079897,0.0001175031,0.000004108568,0.00003212061,6.597871e-7,0.000076936],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003239476,"threshold_uncertainty_score":0.007778466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04387556233235692,"score_gpt":0.4588760357133568,"score_spread":0.4150004733809999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}