{"id":"W4403827753","doi":"10.1371/journal.pone.0312775","title":"Fecal microbiota transplantation from protozoa-exposed donors downregulates immune response in a germ-free mouse model, its role in immune response and physiology of the intestine","year":2024,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Victoria; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México; Fundación IMSS; Instituto Mexicano del Seguro Social; Consejo Nacional de Ciencia y Tecnología","keywords":"Biology; Immune system; Ileum; Immunology; FOXP3; Intestinal mucosa; Duodenum; Spleen; Microbiology; Internal medicine; Medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002059654,0.0007367258,0.0004776061,0.0006114597,0.0002018635,0.0004795129,0.0002383005,0.0006600624,0.001683027],"category_scores_gemma":[0.0001668326,0.0002751718,0.0004506421,0.0001918887,0.0004296975,0.0004154847,0.0002510817,0.001623619,0.0003861418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002193632,"about_ca_system_score_gemma":0.0002169303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002950353,"about_ca_topic_score_gemma":0.0004841222,"domain_scores_codex":[0.9997129,0.00004005207,0.00002751006,0.0000774792,0.0000700017,0.00007202769],"domain_scores_gemma":[0.9997178,0.0000181784,0.00009097056,0.00002682144,0.0000189705,0.0001273006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006320189,0.0002541214,0.0003255508,0.00005657485,0.000008444636,0.0001090574,0.00002422094,0.00003997577,0.9970797,0.00004737439,0.00003902393,0.001384026],"study_design_scores_gemma":[0.0001979893,0.007085358,0.02316435,0.00006360669,0.00009310622,0.0009235102,0.0001737268,0.001327738,0.9635096,0.0001632352,0.003280523,0.00001722867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962299,0.001438857,0.0009966069,0.0001369096,0.00006644122,0.00003381858,0.0002653584,0.0001016154,0.0007304943],"genre_scores_gemma":[0.9927287,0.001407974,0.001606016,0.0001565326,0.00004159897,0.00008889753,0.0004546824,0.00004432163,0.003471229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001683027,"threshold_uncertainty_score":0.005630314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01526696241896372,"score_gpt":0.227089911679183,"score_spread":0.2118229492602193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}