{"id":"W4403831897","doi":"10.1681/asn.2024g9xf6k34","title":"Next-Level Approach to Antibody-Mediated Rejection and T Cell-Mediated Rejection Diagnosis in Kidney Transplantation: Dynamic Duo of Urine CXCL10 and Donor-Derived Cell-Free DNA","year":2024,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; McGill University Health Centre; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Transplantation; Kidney transplantation; Cell-free fetal DNA; Medicine; Graft rejection; Antibody; Kidney; Urine; Immunology; Urology; Biology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00339074,0.0004459479,0.0009181118,0.002552903,0.0004410656,0.001694815,0.0005669097,0.0009600025,0.001798813],"category_scores_gemma":[0.003433945,0.0003655689,0.0006177571,0.0008664082,0.0003979802,0.0005668158,0.001073154,0.001243351,0.0006744411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006788141,"about_ca_system_score_gemma":0.0005797698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001188732,"about_ca_topic_score_gemma":0.003264419,"domain_scores_codex":[0.9976649,0.0009545225,0.0000998828,0.0004850984,0.0006362985,0.000159275],"domain_scores_gemma":[0.9977584,0.0007527388,0.00051855,0.0002046998,0.0004856246,0.0002799187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003669932,0.001229462,0.4169279,0.001430839,0.00088375,0.000774895,0.0007399817,0.005317667,0.3354636,0.002359287,0.006276527,0.2249263],"study_design_scores_gemma":[0.0001636541,0.006084093,0.5533595,0.0005703255,0.0008821113,0.006556317,0.0008481931,0.1232369,0.266906,0.005639136,0.03548249,0.0002712604],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.718017,0.01706505,0.2405806,0.001790776,0.0006386893,0.001096761,0.003736629,0.003151061,0.01392348],"genre_scores_gemma":[0.8299927,0.001716881,0.1617302,0.001021772,0.0001897263,0.0006905051,0.001373332,0.0001089741,0.003175884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00339074,"threshold_uncertainty_score":0.01793218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01704846306099266,"score_gpt":0.2765095902588414,"score_spread":0.2594611271978488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}