{"id":"W4403832866","doi":"10.1681/asn.20244pzx4j11","title":"Long-Term Results from the ORIGIN Phase 2b Study of Atacicept for the Treatment of IgA Nephropathy (IgAN)","year":2024,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Nephropathy; Medicine; Term (time); Immunology; Internal medicine; Pediatrics; Endocrinology; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01004799,0.001327827,0.002169679,0.0003516403,0.0006250928,0.001083822,0.0009173305,0.001635432,0.003194137],"category_scores_gemma":[0.003823183,0.0004988408,0.00204964,0.0004227748,0.0007102232,0.0009585844,0.0006780949,0.003247374,0.0008112678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007619511,"about_ca_system_score_gemma":0.001261845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007881642,"about_ca_topic_score_gemma":0.001578273,"domain_scores_codex":[0.997725,0.001178664,0.0001774662,0.0002792702,0.0004111784,0.000228478],"domain_scores_gemma":[0.9946465,0.00114578,0.001678647,0.00047811,0.0008500706,0.001200977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8801172,0.01854399,0.01947476,0.0008455899,0.005337793,0.0001338045,0.0002514517,0.0009529108,0.01293302,0.00009917567,0.004132854,0.05717736],"study_design_scores_gemma":[0.494233,0.3652474,0.1233896,0.0001474379,0.005613067,0.0004132372,0.00009911715,0.001026584,0.004428184,0.0002125486,0.005109172,0.00008076771],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.979484,0.009808822,0.001203632,0.0004720997,0.000124311,0.001749499,0.004903689,0.0001223313,0.002131602],"genre_scores_gemma":[0.9812906,0.002786141,0.001876412,0.001258645,0.0001974782,0.00160002,0.008454627,0.00005660845,0.002479489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01004799,"threshold_uncertainty_score":0.05313945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0343817025284529,"score_gpt":0.3518368953563299,"score_spread":0.317455192827877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}