{"id":"W4403843268","doi":"10.3390/cells13211773","title":"Mitochondrial Dynamics Drive Muscle Stem Cell Progression from Quiescence to Myogenic Differentiation","year":2024,"lang":"en","type":"review","venue":"Cells","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Universities Space Research Association","keywords":"Cell biology; Cell fate determination; Mitochondrion; Stem cell; mitochondrial fusion; Biology; Cellular differentiation; Skeletal muscle; Cell; Myocyte; Cell metabolism; Regeneration (biology); Anatomy; Transcription factor; Biochemistry; Mitochondrial DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000305646,0.0007705498,0.0008114448,0.00182066,0.0002857091,0.001041484,0.0006961434,0.001016173,0.003976749],"category_scores_gemma":[0.0004192379,0.0002177239,0.0003196845,0.001611096,0.000374509,0.001238961,0.000854607,0.001332318,0.003325837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006664298,"about_ca_system_score_gemma":0.0007898524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006975224,"about_ca_topic_score_gemma":0.001319309,"domain_scores_codex":[0.9999046,0.00001330806,0.00001216128,0.00002000671,0.00003704473,0.00001287237],"domain_scores_gemma":[0.9998872,0.00003815589,0.00001659348,0.00000339254,0.00003762178,0.00001701478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008146629,0.00004267932,0.0001402543,0.0166938,0.0000589793,0.0002668048,0.00006884537,0.0004583832,0.006719864,0.009445623,0.03006286,0.9359605],"study_design_scores_gemma":[0.000008266464,0.00005018066,0.0005105265,0.001924437,0.00004681573,0.0007783686,0.00004430659,0.00007375426,0.001091974,0.00267061,0.9927865,0.00001428211],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001599395,0.9972814,0.00025262,0.0002998704,0.0002246761,0.000004650032,0.00003472874,0.0000160348,0.001726011],"genre_scores_gemma":[0.0007602961,0.9980604,0.0001537141,0.0001268519,0.0000836693,0.000005317322,0.00003661633,0.000002228676,0.0007708419],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003976749,"threshold_uncertainty_score":0.01330358,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01225641469118472,"score_gpt":0.2849373235211617,"score_spread":0.272680908829977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}