{"id":"W4403843268","doi":"10.3390/cells13211773","title":"Mitochondrial Dynamics Drive Muscle Stem Cell Progression from Quiescence to Myogenic Differentiation","year":2024,"lang":"en","type":"review","venue":"Cells","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Universities Space Research Association","keywords":"Cell biology; Cell fate determination; Mitochondrion; Stem cell; mitochondrial fusion; Biology; Cellular differentiation; Skeletal muscle; Cell; Myocyte; Cell metabolism; Regeneration (biology); Anatomy; Transcription factor; Biochemistry; Mitochondrial DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000385931,0.0004060878,0.0005821722,0.00006810189,0.00006855967,0.00004439873,0.0003797682,0.0006107042,0.00003837412],"category_scores_gemma":[0.000006471815,0.000330295,0.0004229769,0.0001289038,0.0000487657,0.000002756941,0.0003163232,0.0002490352,0.0004250743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004746344,"about_ca_system_score_gemma":0.0001533248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001043043,"about_ca_topic_score_gemma":0.00003178468,"domain_scores_codex":[0.9982771,0.0001385173,0.0003548207,0.0008167663,0.0001262322,0.0002865916],"domain_scores_gemma":[0.9990978,0.00002282399,0.0001727522,0.000549024,0.00003642102,0.0001212281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000578023,0.000171476,0.000002051006,0.004696461,0.0002059494,0.000006724365,0.00009124439,0.000007627068,0.06721847,0.00002172886,0.0140371,0.9134834],"study_design_scores_gemma":[0.0002502701,0.0002726287,0.000008941622,0.002391948,0.0008546435,8.626751e-7,0.00004904334,0.00005340168,0.007269653,0.00006569408,0.9880791,0.0007037987],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004127597,0.9914607,0.0006766436,0.00001174701,0.002200334,0.0008713993,0.0003448457,0.0000314768,0.0002751993],"genre_scores_gemma":[0.00179476,0.9926264,0.0002296904,0.00005223629,0.0006939778,0.0001644492,0.003024747,0.00007374235,0.001339989],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.974042,"threshold_uncertainty_score":0.9999149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01225641469118472,"score_gpt":0.2849373235211617,"score_spread":0.272680908829977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}