{"id":"W4403850203","doi":"10.4103/sjg.sjg_360_24","title":"The treatment naïve microbiome of pediatric ulcerative colitis and microbial therapeutics: A humbling challenge","year":2024,"lang":"en","type":"article","venue":"Saudi Journal of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Texas Children's Hospital; U.S. Department of Agriculture","keywords":"Medicine; Ulcerative colitis; Microbiome; Fecal bacteriotherapy; Intensive care medicine; Bioinformatics; Microbiology; Internal medicine; Disease; Clostridium difficile; Antibiotics; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002806292,0.0001455953,0.000247733,0.0001022591,0.0000927681,0.00002856965,0.0001304264,0.00009758723,0.000006035602],"category_scores_gemma":[0.000006473705,0.00009712607,0.0001447719,0.00005004021,0.0001604759,0.000004946564,0.00004142597,0.0001405613,0.000001403449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003660995,"about_ca_system_score_gemma":0.0001208651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000638458,"about_ca_topic_score_gemma":0.0001928428,"domain_scores_codex":[0.9989291,0.00015429,0.0004097171,0.0001709853,0.00005239113,0.0002835111],"domain_scores_gemma":[0.999445,0.00003561301,0.0002120359,0.000119136,0.0001250947,0.00006311397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003152313,0.0002708416,0.005838942,0.0001487866,0.001002015,0.00005174799,0.001227669,0.000006457249,0.9804465,0.0000911262,0.001672989,0.006090654],"study_design_scores_gemma":[0.02167657,0.1502844,0.1249549,0.0005908187,0.002508886,0.01243277,0.003044466,0.00009245286,0.1707659,0.0009978557,0.5115679,0.001083057],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849313,0.01265843,0.0002034347,0.001527531,0.0004910677,0.0001221156,0.00004187266,0.000002747244,0.00002146493],"genre_scores_gemma":[0.9614963,0.03734114,0.0002659031,0.0001842284,0.0006093408,0.000002678896,0.000007592723,0.00001607851,0.00007677162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8096806,"threshold_uncertainty_score":0.3960686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01511579532111107,"score_gpt":0.2773375243387446,"score_spread":0.2622217290176336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}