{"id":"W4403852522","doi":"10.17615/0jt9-4n49","title":"Genetic variants for head size share genes and pathways with cancer","year":2024,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Japan Society for the Promotion of Science; National Health and Medical Research Council; National Center for Advancing Translational Sciences; Medical Research Council; Canadian Institutes of Health Research; Wake Forest School of Medicine; Macquarie Group Foundation; Universität Greifswald; National Institutes of Health; Heinz Nixdorf Stiftung; Siemens Healthineers; University College London Hospitals NHS Foundation Trust; Ramsay Health Care; Fondation Bettencourt Schueller; Fondation de France; Kaiser Foundation Research Institute; Vetenskapsrådet; Novo Nordisk; Suomen Lääketieteen Säätiö; Bundesministerium für Wissenschaft, Forschung und Wirtschaft; Erasmus Medisch Centrum; ZonMw; Ministry of Education, Culture, Sports, Science and Technology; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; National Center for Research Resources; Agence Nationale de la Recherche; University of Toronto; British Heart Foundation; Australian Schizophrenia Research Bank; Bundesministerium für Bildung und Forschung; National Institute on Aging; Pratt Foundation; National Institute for Health and Care Research; Government of Ontario; Institut National de la Santé et de la Recherche Médicale; University of Minnesota; EU Joint Programme – Neurodegenerative Disease Research; Université de Bordeaux; Compute Canada; European Commission; School of Medicine, Boston University; Northwestern University; Heart and Stroke Foundation of Canada; Sanofi; U.S. Department of Health and Human Services","keywords":"Gene; Genetics; Biology; Head (geology); Computational biology; Evolutionary biology; Paleontology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003612308,0.0001895047,0.0002426449,0.00006917382,0.00008494304,0.0001643187,0.00006135828,0.0001076936,0.0003218543],"category_scores_gemma":[0.00005199885,0.0001427269,0.00005569881,0.0002039815,0.0001147782,0.00018527,0.00004804338,0.000129521,0.000009919131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003889481,"about_ca_system_score_gemma":0.0006113772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006545482,"about_ca_topic_score_gemma":0.000073298,"domain_scores_codex":[0.9990093,0.00001261206,0.000157833,0.0003885382,0.0001660841,0.0002657072],"domain_scores_gemma":[0.9994291,0.0001322259,0.00002658496,0.0002265186,0.00004849077,0.0001371008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004371756,0.0003460563,0.01793921,0.01030072,0.003295787,0.003020033,0.01143404,0.000350659,0.2473264,0.2377322,0.09007297,0.3738101],"study_design_scores_gemma":[0.01219822,0.004533024,0.05767644,0.007840933,0.002455903,0.001408813,0.0009670476,0.01109928,0.1806853,0.06378894,0.6552073,0.00213875],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6711241,0.2945516,0.01308836,0.008700635,0.001715261,0.003063574,0.001567279,0.001258711,0.004930474],"genre_scores_gemma":[0.9167315,0.0009812559,0.07231475,0.002327873,0.001383472,0.0007678648,0.0001396976,0.0002825796,0.00507105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5651343,"threshold_uncertainty_score":0.5820235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02375743336851264,"score_gpt":0.2489308404514436,"score_spread":0.225173407082931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}