{"id":"W4403882302","doi":"10.1007/s00125-024-06298-y","title":"The Type 1 Diabetes T Cell Receptor and B Cell Receptor Repository in the AIRR Data Commons: a practical guide for access, use and contributions through the Type 1 Diabetes AIRR Consortium","year":2024,"lang":"en","type":"article","venue":"Diabetologia","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"University of Colorado School of Medicine, Anschutz Medical Campus; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Universidade de Santiago de Compostela; Leona M. and Harry B. Helmsley Charitable Trust; Diabetes Research and Wellness Foundation; National Institutes of Health","keywords":"T-cell receptor; Biology; Type 1 diabetes; Autoimmunity; breakpoint cluster region; Human leukocyte antigen; Immunology; Type 2 diabetes; Immune system; Cancer research; Genetics; Receptor; Diabetes mellitus; T cell; Endocrinology; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.06458227,0.002154938,0.004306037,0.0122607,0.002362598,0.01391542,0.01083509,0.004677294,0.2002421],"category_scores_gemma":[0.1578749,0.00380162,0.002604256,0.01899712,0.003040476,0.01598815,0.02222094,0.009355064,0.2155769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002926476,"about_ca_system_score_gemma":0.01259171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005325763,"about_ca_topic_score_gemma":0.006479211,"domain_scores_codex":[0.9765909,0.00748601,0.005624146,0.002598297,0.006618425,0.001082256],"domain_scores_gemma":[0.8476486,0.05199396,0.00846513,0.05651752,0.02064166,0.0147331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002168189,0.00009080588,0.0007266504,0.001054468,0.00005837801,0.0002086306,0.000355765,0.000476067,0.001194133,0.009806628,0.92517,0.06064152],"study_design_scores_gemma":[0.0001140046,0.00002854167,0.000680948,0.001014252,0.00001904935,0.0001466181,0.000169564,0.0005715,0.0006066654,0.008690335,0.9878646,0.00009403883],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"methods","genre_scores_codex":[0.001062724,0.001969241,0.1835849,0.0148798,0.004496431,0.004823118,0.6014866,0.134807,0.05289009],"genre_scores_gemma":[0.006755919,0.003333607,0.4000993,0.01312948,0.001932485,0.01317273,0.4455086,0.08177838,0.0342895],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.2002421,"threshold_uncertainty_score":0.6698766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02643178240269575,"score_gpt":0.3108815086051546,"score_spread":0.2844497262024588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}