{"id":"W4403909260","doi":"10.1016/j.clbc.2024.10.017","title":"Another Biosignature for Ductal Carcinoma In Situ—Have We Moved the Needle?","year":2024,"lang":"en","type":"letter","venue":"Clinical Breast Cancer","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; In situ; Ductal carcinoma; Breast cancer; Carcinoma in situ; Surgery; Pathology; Carcinoma; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008747013,0.0007365605,0.001926959,0.0009123594,0.003790244,0.002995898,0.002093932,0.05192707,0.006160712],"category_scores_gemma":[0.02998527,0.0006567339,0.001438378,0.0007568561,0.005613144,0.005350512,0.00194313,0.04170074,0.002666937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004943093,"about_ca_system_score_gemma":0.007152592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006157843,"about_ca_topic_score_gemma":0.01237574,"domain_scores_codex":[0.9938257,0.002527727,0.0007688893,0.0005658978,0.001617474,0.0006943159],"domain_scores_gemma":[0.9807054,0.01220465,0.0009733982,0.0008133481,0.002172301,0.003130898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003935464,0.0002350665,0.003491131,0.0001894293,0.00009598574,0.003335489,0.0002356573,0.0001235774,0.001003825,0.01576989,0.9380724,0.03705407],"study_design_scores_gemma":[0.000575914,0.0004800457,0.003791835,0.0005702158,0.0001466649,0.004059886,0.000931075,0.0005263148,0.0008584552,0.0429903,0.9449103,0.0001588693],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.0004283711,0.00233468,0.0001047964,0.9847122,0.01109228,0.000008273657,0.00002068187,0.000009395781,0.001289284],"genre_scores_gemma":[0.004246067,0.001810975,0.0003598089,0.954623,0.03505677,0.00002861242,0.00002313715,0.00001273718,0.003838915],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.05192707,"threshold_uncertainty_score":0.04625916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03111023548600697,"score_gpt":0.3331387168952305,"score_spread":0.3020284814092236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}