{"id":"W4403916107","doi":"10.1101/2024.10.29.620805","title":"The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Advanced Materials and Mechanics","field":"Engineering","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Pilus; Periplasmic space; Extension (predicate logic); Computer science; Biology; Genetics; Escherichia coli; Programming language","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006537986,0.0002070756,0.0001460739,0.0001718184,0.0002781248,0.0004167511,0.0001852648,0.000389123,0.001063113],"category_scores_gemma":[0.0001748558,0.0001333602,0.0001734991,0.0001495504,0.0002823375,0.0002028264,0.0002459053,0.0004272501,0.0003243892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004288829,"about_ca_system_score_gemma":0.000163456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001137073,"about_ca_topic_score_gemma":0.0007470104,"domain_scores_codex":[0.9999527,0.000005166334,0.000002612967,0.00001585211,0.00001460699,0.000008999855],"domain_scores_gemma":[0.9999332,0.00001411277,0.00002036037,0.000009849803,0.00000701782,0.00001534077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001522324,0.00003002805,0.001991171,0.00006574328,0.00001417187,0.0005483183,0.00006948751,0.0008873016,0.9934205,0.0006967267,0.000347159,0.001777144],"study_design_scores_gemma":[0.00004576734,0.0001358194,0.04625491,0.00003448972,0.00003625501,0.001275907,0.0002345053,0.05130779,0.8914359,0.001114595,0.008099101,0.00002498023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937592,0.0005360608,0.004088209,0.0001899373,0.0000229245,0.000005937218,0.0002454406,0.00009613983,0.001056066],"genre_scores_gemma":[0.9960068,0.0001444596,0.002435092,0.00003959974,0.000005178607,0.000004304322,0.0006012758,0.00001539857,0.0007479481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001137073,"threshold_uncertainty_score":0.00355643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01436905831781498,"score_gpt":0.2184396395938088,"score_spread":0.2040705812759938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}