{"id":"W4403917403","doi":"10.3390/jof10110749","title":"The Influence of Aspergillus fumigatus Fatty Acid Oxygenases PpoA and PpoC on Caspofungin Susceptibility","year":2024,"lang":"en","type":"article","venue":"Journal of Fungi","topic":"Mycotoxins in Agriculture and Food","field":"Agricultural and Biological Sciences","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Azrieli Foundation; Conselho Nacional de Desenvolvimento Científico e Tecnológico; International Development Research Centre; Fundação de Amparo à Pesquisa do Estado de São Paulo; Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Aspergillus fumigatus; Caspofungin; Oxygenase; Chemistry; Aspergillus; Fungi imperfecti; Microbiology; Biology; Biochemistry; Gene; Antifungal","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001120716,0.0003475174,0.0002783606,0.000239243,0.0001089128,0.000397172,0.0001404527,0.0002643759,0.0005474461],"category_scores_gemma":[0.0002844973,0.000102177,0.0002294581,0.0001930625,0.0001834435,0.000202,0.0002218293,0.0003529199,0.000190258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002415974,"about_ca_system_score_gemma":0.0001927928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002493337,"about_ca_topic_score_gemma":0.002118374,"domain_scores_codex":[0.9996523,0.00004828845,0.00003916546,0.00006962156,0.0001013985,0.00008923318],"domain_scores_gemma":[0.9998092,0.00003901067,0.00005660645,0.00001781947,0.00002668865,0.00005069308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001040285,0.00002552824,0.001008557,0.00001889776,0.000005629019,0.00003873547,0.00001347226,0.00003685309,0.9977362,0.00001505942,0.00002201403,0.0009750376],"study_design_scores_gemma":[0.00001527487,0.0005912919,0.06665777,0.00001130967,0.0000490881,0.0004856087,0.0002180571,0.001001588,0.9295355,0.00004945753,0.001370543,0.00001442773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979635,0.0006751873,0.0004304926,0.00006773273,0.00001139426,0.000015545,0.0003330331,0.00001900495,0.000484092],"genre_scores_gemma":[0.9982135,0.0002936622,0.000672062,0.00004765978,0.00000505861,0.00001653865,0.0003553838,0.000006955582,0.0003890629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002493337,"threshold_uncertainty_score":0.004957616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01082632683344427,"score_gpt":0.2211549025661406,"score_spread":0.2103285757326963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}