{"id":"W4403917403","doi":"10.3390/jof10110749","title":"The Influence of Aspergillus fumigatus Fatty Acid Oxygenases PpoA and PpoC on Caspofungin Susceptibility","year":2024,"lang":"en","type":"article","venue":"Journal of Fungi","topic":"Mycotoxins in Agriculture and Food","field":"Agricultural and Biological Sciences","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Azrieli Foundation; Conselho Nacional de Desenvolvimento Científico e Tecnológico; International Development Research Centre; Fundação de Amparo à Pesquisa do Estado de São Paulo; Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Aspergillus fumigatus; Caspofungin; Oxygenase; Chemistry; Aspergillus; Fungi imperfecti; Microbiology; Biology; Biochemistry; Gene; Antifungal","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005424311,0.0001262103,0.0002031305,0.00001211503,0.0001409125,0.00009182213,0.000254016,0.00008316991,0.00007160993],"category_scores_gemma":[0.0001297081,0.00003272765,0.0001579685,0.0002718396,0.00009317148,0.0001414758,0.00004853167,0.0002744678,0.000009914756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002573551,"about_ca_system_score_gemma":0.00001617973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002171148,"about_ca_topic_score_gemma":0.0001471759,"domain_scores_codex":[0.9988798,0.00007763656,0.0003858045,0.0001541768,0.0003115319,0.000191015],"domain_scores_gemma":[0.9989659,0.0005657605,0.0001570334,0.0000629989,0.0001414852,0.0001068401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001118563,0.00006591185,0.0031166,0.00002653093,0.00006504023,0.000044048,0.0001571121,0.00001799125,0.8652139,0.001193799,0.002359882,0.1276273],"study_design_scores_gemma":[0.0001764333,0.002727635,0.7982908,0.0003595258,0.00008085238,0.0003585544,0.0007619974,0.00002247397,0.116059,0.002146018,0.07874913,0.0002676409],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852329,0.01295376,0.000001055939,0.0009176902,0.000247641,0.0000885491,0.00004304445,0.00001323473,0.0005021384],"genre_scores_gemma":[0.9972559,0.002159702,0.00005497613,0.00009685806,0.000340136,0.000001341367,0.000002032275,8.229497e-7,0.0000882222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7951742,"threshold_uncertainty_score":0.1334595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01082632683344427,"score_gpt":0.2211549025661406,"score_spread":0.2103285757326963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}