{"id":"W4403926357","doi":"10.1016/j.vaccine.2024.126463","title":"SARS-CoV-2 spike-based virus-like particles incorporate influenza H1/N1 antigens and induce dual immunity in mice","year":2024,"lang":"en","type":"article","venue":"Vaccine","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Institute for Nanotechnology; National Research Council Canada","funders":"National Research Council Canada; Natural Sciences and Engineering Research Council of Canada","keywords":"Virology; Immunity; Spike (software development); Virus; Antigen; Biology; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004973732,0.001177939,0.0005931256,0.0009262122,0.0002588271,0.0005218213,0.000492888,0.001235168,0.001482948],"category_scores_gemma":[0.0001561668,0.0005939263,0.000854809,0.0002172919,0.0004391399,0.0005235124,0.0003832143,0.002570225,0.0009945997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004304955,"about_ca_system_score_gemma":0.0002819905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003975273,"about_ca_topic_score_gemma":0.0005036905,"domain_scores_codex":[0.9994742,0.00007616915,0.00006092172,0.0001245827,0.0001095725,0.0001545838],"domain_scores_gemma":[0.9997614,0.00003072943,0.00006322389,0.00004337845,0.00002933093,0.00007201003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003092119,0.0003831926,0.0001165256,0.00004436618,0.00001322014,0.00003813557,0.00003039334,0.0001031684,0.9979072,0.000185309,0.00008485287,0.0007846141],"study_design_scores_gemma":[0.0001650125,0.003465622,0.001959741,0.00002171671,0.00005153705,0.0002806534,0.00003719041,0.002050471,0.988335,0.0001471584,0.00347512,0.00001074908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878363,0.0008329984,0.006008109,0.0002853164,0.0001504372,0.0003377267,0.001143066,0.0004022724,0.003003746],"genre_scores_gemma":[0.9812084,0.001056132,0.006901872,0.0003644755,0.00006381124,0.0003887152,0.001750981,0.00009334732,0.008172191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001482948,"threshold_uncertainty_score":0.004960895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06874464890831998,"score_gpt":0.3611266295306975,"score_spread":0.2923819806223775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}