{"id":"W4403939905","doi":"10.1038/s41598-024-77963-w","title":"Reflection mode polarimetry guides laser mass spectrometry to diagnostically important regions of human breast cancer tissue","year":2024,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Optical Polarization and Ellipsometry","field":"Engineering","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University Health Network; Princess Margaret Cancer Centre; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Breast cancer; Human breast; Polarimetry; Mass spectrometry; Reflection (computer programming); Laser; Cancer; Medicine; Optics; Pathology; Computer science; Chemistry; Physics; Chromatography; Internal medicine; Scattering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004936146,0.0005831654,0.0002379593,0.0004774689,0.0002400613,0.0005927156,0.0002946648,0.0004617396,0.00157381],"category_scores_gemma":[0.0008866886,0.0003144128,0.0001449388,0.0003775892,0.0007932014,0.0005472382,0.0005042417,0.0007181167,0.00091853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002510773,"about_ca_system_score_gemma":0.0003129328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002873648,"about_ca_topic_score_gemma":0.000716301,"domain_scores_codex":[0.9997384,0.00007207508,0.000009692581,0.00007736171,0.00007600619,0.00002643309],"domain_scores_gemma":[0.9994239,0.0002470125,0.0001588127,0.0000659418,0.00008197423,0.00002248573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005784747,0.000005994286,0.000485581,0.00005137343,0.000003143713,0.00003449421,0.00004113494,0.0002012704,0.991417,0.0003837325,0.00009456169,0.007223856],"study_design_scores_gemma":[0.000003537712,0.00006449322,0.001497852,0.00000908813,0.00000600644,0.0002753053,0.00007674801,0.002002433,0.9935514,0.0003223096,0.002182688,0.000008111708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6151162,0.005391045,0.3674601,0.0009236541,0.0001367977,0.0001005669,0.0005002437,0.001518589,0.008852834],"genre_scores_gemma":[0.8141219,0.004521322,0.1768105,0.0003379652,0.00007940152,0.000099551,0.0002714787,0.0002559239,0.003501997],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00157381,"threshold_uncertainty_score":0.005264878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01250493599534438,"score_gpt":0.2978170490620481,"score_spread":0.2853121130667037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}