{"id":"W4404019665","doi":"10.3390/cells13211812","title":"Regulatory Mechanism of Protein Crotonylation and Its Relationship with Cancer","year":2024,"lang":"en","type":"review","venue":"Cells","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Natural Science Foundation of China","keywords":"Mechanism (biology); Non-histone protein; Histone; Cancer; Biology; Prostate cancer; Computational biology; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001385347,0.000194937,0.0003398828,0.00005508013,0.00003051484,0.00001357898,0.00008193273,0.000300821,0.00002513018],"category_scores_gemma":[0.0000111677,0.0001438939,0.00008855746,0.00008728055,0.00003150793,0.00000193468,0.00005947317,0.0001436573,0.00001454185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001278053,"about_ca_system_score_gemma":0.0002265867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003352005,"about_ca_topic_score_gemma":0.000003719992,"domain_scores_codex":[0.9992132,0.00006786871,0.0002159766,0.0003050433,0.00009036233,0.0001075773],"domain_scores_gemma":[0.9995314,0.000007870995,0.0001651947,0.0002052022,0.0000460246,0.00004422984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009745658,0.0001146568,0.00001128385,0.2216388,0.001064202,0.00002603281,0.0002639384,0.000007618472,0.2008152,0.03956225,0.001604326,0.5347943],"study_design_scores_gemma":[0.0001032642,0.000140074,0.000001269866,0.007653607,0.0004015011,0.00001042968,0.000003575522,0.000005050245,0.1636143,0.0002760958,0.8275192,0.0002715552],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001107883,0.9967867,0.00004451436,0.000005769121,0.00007100136,0.001180245,0.0001007791,0.000009751359,0.0006933745],"genre_scores_gemma":[0.004066534,0.990258,0.000169697,0.000006733138,0.0001436804,0.0003971402,0.0001082105,0.00004872891,0.004801261],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8259149,"threshold_uncertainty_score":0.5867825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03695995246031399,"score_gpt":0.296398892972642,"score_spread":0.259438940512328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}