{"id":"W4404019665","doi":"10.3390/cells13211812","title":"Regulatory Mechanism of Protein Crotonylation and Its Relationship with Cancer","year":2024,"lang":"en","type":"review","venue":"Cells","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Natural Science Foundation of China","keywords":"Mechanism (biology); Non-histone protein; Histone; Cancer; Biology; Prostate cancer; Computational biology; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003572312,0.0007196441,0.0008265069,0.001970981,0.0002495431,0.0007824792,0.0006550667,0.0009365876,0.001955109],"category_scores_gemma":[0.0003768693,0.00022774,0.0003355233,0.001709914,0.0005097992,0.001061024,0.0005712582,0.001162477,0.001497137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007125618,"about_ca_system_score_gemma":0.0007500984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00067381,"about_ca_topic_score_gemma":0.001003303,"domain_scores_codex":[0.9998816,0.0000186573,0.00001626915,0.00002771988,0.00003829216,0.00001751108],"domain_scores_gemma":[0.9998944,0.00004106149,0.00001835464,0.000004442404,0.00002844032,0.00001328819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001053082,0.00006965027,0.0003434531,0.01314239,0.0001047059,0.0005522194,0.00006269215,0.0006555882,0.005112338,0.01036156,0.02741116,0.9420789],"study_design_scores_gemma":[0.00001314543,0.00007970084,0.001092897,0.001436358,0.00007037191,0.002532254,0.00004389786,0.0001341954,0.00156402,0.003313419,0.9896992,0.00002072155],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001144462,0.9988371,0.0001287316,0.0001619466,0.000111413,0.000002191948,0.00001011285,0.00000640022,0.000627697],"genre_scores_gemma":[0.0007834293,0.9984545,0.00009981277,0.00009979801,0.00009434135,0.000003444685,0.00001865087,0.000001002143,0.0004450692],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001970981,"threshold_uncertainty_score":0.006540537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03695995246031399,"score_gpt":0.296398892972642,"score_spread":0.259438940512328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}