{"id":"W4404024063","doi":"10.1001/jamaneurol.2024.3733","title":"Deferiprone in Alzheimer Disease","year":2024,"lang":"en","type":"article","venue":"JAMA Neurology","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Deferiprone; Placebo; Medicine; Cognitive decline; Neuropsychology; Adverse effect; Randomized controlled trial; Internal medicine; Cognition; Pediatrics; Psychology; Psychiatry; Disease; Dementia; Pathology; Thalassemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001032863,0.0002700187,0.0005459618,0.0001591582,0.0001674914,0.0003305385,0.0002208193,0.0004937535,0.002271635],"category_scores_gemma":[0.0008942939,0.00006679826,0.0002105092,0.0001555386,0.0002798602,0.0002065459,0.0001665256,0.0007937529,0.0004621073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002338946,"about_ca_system_score_gemma":0.0005435212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006031187,"about_ca_topic_score_gemma":0.00109346,"domain_scores_codex":[0.9997756,0.0001148561,0.00002457239,0.00002218148,0.00004879947,0.00001402807],"domain_scores_gemma":[0.9997085,0.0001180407,0.00007724616,0.0000096364,0.00003257146,0.00005406039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01854476,0.000996554,0.006590732,0.007563284,0.0003068252,0.0007571388,0.0001742631,0.0002875714,0.009012038,0.002694807,0.02646715,0.9266049],"study_design_scores_gemma":[0.04980797,0.06538738,0.1383295,0.009432056,0.002357642,0.009733661,0.0003796945,0.001662477,0.006855671,0.009462194,0.7065026,0.00008914877],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.07920729,0.8956802,0.0006743069,0.01107807,0.002193977,0.0002392981,0.0002427299,0.00005510084,0.01062903],"genre_scores_gemma":[0.5416142,0.4258243,0.002130865,0.0141908,0.005883882,0.0004127999,0.0004310728,0.000008302697,0.009503783],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002271635,"threshold_uncertainty_score":0.007599354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03271760043041262,"score_gpt":0.3268233598472526,"score_spread":0.29410575941684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}