{"id":"W4404070910","doi":"10.3390/vetsci11110540","title":"Longitudinal Study of Transcriptomic Changes Occurring over Six Weeks of CHOP Treatment in Canine Lymphoma Identifies Prognostic Subtypes","year":2024,"lang":"en","type":"article","venue":"Veterinary Sciences","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Ontario Centres of Excellence","keywords":"CHOP; Lymphoma; Transcriptome; Gene; Biology; Canine Lymphoma; Internal medicine; Chemotherapy; Oncology; Gene expression; Immunology; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002466859,0.0001081355,0.0003361178,0.0004100534,0.0001860783,0.0003741568,0.00009048302,0.0001820034,0.0005645865],"category_scores_gemma":[0.0004421512,0.00008203432,0.0001996667,0.0005218482,0.000144349,0.0001677664,0.0002292336,0.0002768167,0.0001757813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002071713,"about_ca_system_score_gemma":0.0001196984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005947695,"about_ca_topic_score_gemma":0.001280969,"domain_scores_codex":[0.9998639,0.00002136382,0.000008500891,0.00004214104,0.00003052461,0.00003366133],"domain_scores_gemma":[0.9997569,0.00005056451,0.00008982724,0.00001718544,0.00004637486,0.00003920199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002406977,0.0001231469,0.6776245,0.0001218423,0.0001893028,0.0003410628,0.0004436548,0.0006612237,0.2913904,0.00008330121,0.000632762,0.02598185],"study_design_scores_gemma":[0.000007728779,0.000249691,0.9909656,0.000006432448,0.00005765919,0.0003419983,0.0002469138,0.0005959102,0.006374966,0.00005361072,0.001092803,0.000006674542],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986448,0.0003713932,0.0002968756,0.00002538606,0.000003138755,0.00000762251,0.0004713926,0.000006693297,0.0001728051],"genre_scores_gemma":[0.9969517,0.0002516021,0.0003905334,0.00004149959,0.000007453037,0.00002568571,0.001980658,0.000006011704,0.0003447303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005947695,"threshold_uncertainty_score":0.001888692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03892918772139458,"score_gpt":0.3158960228091031,"score_spread":0.2769668350877085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}