{"id":"W4404072969","doi":"10.3390/cancers16223726","title":"LKB1 and STRADα Promote Epithelial Ovarian Cancer Spheroid Cell Invasion","year":2024,"lang":"en","type":"article","venue":"Cancers","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Ovarian Cancer Canada; Western University","funders":"London Health Sciences Foundation","keywords":"Spheroid; Matrigel; Invadopodia; Cancer research; Cell biology; Metastasis; Biology; HEK 293 cells; Ovarian cancer; Cell culture; Cancer; Angiogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001941098,0.0002949155,0.0003557754,0.0002450709,0.0001988745,0.0003970465,0.0001361675,0.0003033072,0.001720121],"category_scores_gemma":[0.00009593842,0.0001802179,0.0003897881,0.0001913269,0.0002019212,0.0002365989,0.0003021902,0.0007933064,0.0006998019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000427315,"about_ca_system_score_gemma":0.0003825482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001783294,"about_ca_topic_score_gemma":0.002995759,"domain_scores_codex":[0.9997992,0.00003571542,0.00002177376,0.00002744991,0.00006179469,0.00005411079],"domain_scores_gemma":[0.9998943,0.00002066009,0.00001822237,0.00001606685,0.00001408804,0.00003667633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002026527,0.0000851411,0.0002436442,0.0001108936,0.00001077428,0.00005743978,0.00007951031,0.0002205875,0.996299,0.0002004113,0.000581101,0.001908832],"study_design_scores_gemma":[0.00007292368,0.0004200163,0.007716959,0.00002128849,0.00002459659,0.0002562982,0.0001233377,0.003422413,0.9743594,0.00009304559,0.01347985,0.000009820213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838982,0.003610098,0.004362821,0.0004616168,0.00009735525,0.00008479402,0.002088093,0.0003519897,0.005044954],"genre_scores_gemma":[0.9884638,0.001352828,0.002556518,0.0001590377,0.000008813196,0.0001015183,0.002139235,0.00004740163,0.005170743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001783294,"threshold_uncertainty_score":0.005754411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007786240320936715,"score_gpt":0.2366294808233276,"score_spread":0.2288432405023909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}