{"id":"W4404094196","doi":"10.1016/j.scr.2024.103608","title":"Generation of an iPSC cell line (VANYHHi001-A) from a patient with cardiac arrythmias carrying CACNA1D, SCN5A, and DSP variants","year":2024,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut Universitaire en Santé Mentale de Québec","funders":"National Heart, Lung, and Blood Institute; Biomedical Laboratory Research and Development, VA Office of Research and Development; U.S. Department of Defense","keywords":"Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002496482,0.0002382067,0.0003204846,0.0003747129,0.000292352,0.0003527922,0.0003420605,0.0005895172,0.00271062],"category_scores_gemma":[0.0003022409,0.0001434276,0.0003566708,0.000261273,0.0001940984,0.000143371,0.0003700649,0.0008138395,0.001013674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001072754,"about_ca_system_score_gemma":0.0002606112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005182852,"about_ca_topic_score_gemma":0.000568732,"domain_scores_codex":[0.9998515,0.0000124465,0.00002972583,0.00004212043,0.00004247524,0.000021854],"domain_scores_gemma":[0.9998999,0.00002881123,0.000008816357,0.00001774467,0.00001442737,0.00003031613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001859989,0.0002368185,0.005191552,0.0001167995,0.00004095262,0.009657039,0.0003402151,0.0005027145,0.9640216,0.001582601,0.00146603,0.01665764],"study_design_scores_gemma":[0.0003970021,0.001989214,0.04316692,0.00016453,0.0002984158,0.07042625,0.0004921732,0.00972995,0.7893574,0.001231439,0.08263608,0.0001106003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9499744,0.001686346,0.02881044,0.0004920265,0.0004471714,0.0007886487,0.005709766,0.000282955,0.0118083],"genre_scores_gemma":[0.9401838,0.002136638,0.02788176,0.0005083743,0.0001232615,0.0006221193,0.01750064,0.0001348169,0.01090857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00271062,"threshold_uncertainty_score":0.009067893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0567800709550975,"score_gpt":0.3242689118241206,"score_spread":0.2674888408690231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}