{"id":"W4404096900","doi":"10.1183/13993003.congress-2024.pa4778","title":"Efficacy and safety of axatilimab at 3 different doses in patients with chronic graft-versus-host disease (cGVHD) and related bronchiolitis obliterans syndrome (BOS): results of a pivotal phase 2 study","year":2024,"lang":"en","type":"article","venue":"","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital","funders":"","keywords":"Bronchiolitis obliterans; Graft-versus-host disease; Medicine; Disease; Host (biology); Immunology; Internal medicine; Biology; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001765348,0.001161088,0.001587182,0.0002578911,0.000390057,0.001022912,0.0005776071,0.001064465,0.002103652],"category_scores_gemma":[0.00110118,0.0004183157,0.001486114,0.0002437104,0.0005639505,0.001045244,0.0002641018,0.002664046,0.0006967265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007082162,"about_ca_system_score_gemma":0.0007696116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003547981,"about_ca_topic_score_gemma":0.0008943046,"domain_scores_codex":[0.9995083,0.0002236424,0.00003510826,0.0000896986,0.00005703194,0.00008616733],"domain_scores_gemma":[0.9992481,0.0001594932,0.000186029,0.00006438414,0.00004769853,0.0002942995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7315155,0.03566226,0.01087322,0.0009427613,0.001701573,0.000278026,0.000369414,0.002569732,0.05099842,0.0002384965,0.006477858,0.1583727],"study_design_scores_gemma":[0.4785808,0.4729668,0.03627641,0.00007980275,0.0008992308,0.0004148758,0.00007861078,0.001969649,0.004522513,0.0002700719,0.00387937,0.00006189338],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921326,0.004289132,0.0003223836,0.0004956473,0.0001230385,0.0004715474,0.0006279509,0.00006590541,0.001471865],"genre_scores_gemma":[0.9940613,0.001340655,0.0008155954,0.0009878705,0.0002063045,0.0006632537,0.001133059,0.00002502691,0.000766945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002103652,"threshold_uncertainty_score":0.009336233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0117740186676639,"score_gpt":0.2974325438901369,"score_spread":0.285658525222473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}