{"id":"W4404105468","doi":"10.1038/s41409-024-02447-4","title":"Measurable residual mutated IDH1 before allogeneic transplant for acute myeloid leukemia","year":2024,"lang":"en","type":"article","venue":"Bone Marrow Transplantation","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; U.S. Navy; Health Resources and Services Administration; Syndax Pharmaceuticals; Office of Naval Research; Jazz Pharmaceuticals; Genentech; AstraZeneca; National Institutes of Health; U.S. Department of Health and Human Services; Foundation for the National Institutes of Health; Amgen; Gilead Sciences; U.S. Department of Defense","keywords":"NPM1; IDH1; Medicine; Myeloid leukemia; Internal medicine; Oncology; Minimal residual disease; IDH2; Transplantation; Hematopoietic stem cell transplantation; Leukemia; Myeloid; Mutation; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002977364,0.0001031401,0.0001782847,0.0002735474,0.0002273755,0.00034898,0.0001983099,0.000159725,0.0007677737],"category_scores_gemma":[0.00101203,0.00008456683,0.0001051811,0.0002454153,0.0002158022,0.0002123961,0.0002186972,0.0003815979,0.0001695033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002905808,"about_ca_system_score_gemma":0.0002708291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00134225,"about_ca_topic_score_gemma":0.002025732,"domain_scores_codex":[0.9997535,0.00004494387,0.00002489765,0.00006375185,0.00005981716,0.00005298329],"domain_scores_gemma":[0.9995472,0.0001081632,0.0001625076,0.00005004118,0.0000342612,0.0000977835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005952255,0.00008448854,0.9888638,0.00001431428,0.0000103184,0.0003114624,0.00009994081,0.00005492476,0.004097751,0.00002404231,0.00008068883,0.005763092],"study_design_scores_gemma":[0.00001648784,0.001189056,0.9938013,0.000007392113,0.00002083482,0.001485292,0.0001456977,0.0002178012,0.002509311,0.00004794858,0.0005548325,0.000004097129],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995182,0.0001357529,0.00008334465,0.00001173335,0.000002773173,0.000006729232,0.00006453872,0.000002756385,0.0001743099],"genre_scores_gemma":[0.9996694,0.00004476856,0.00006928456,0.00001541954,0.000004167013,0.000003794289,0.0001280632,0.000001079381,0.000063969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00134225,"threshold_uncertainty_score":0.002668858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01979265900489028,"score_gpt":0.2970428500041754,"score_spread":0.2772501909992851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}