{"id":"W4404108769","doi":"10.1128/aem.01299-24","title":"Adaptive immunity in <i>Mus musculus</i> influences the acquisition and abundance of <i>Borrelia burgdorferi</i> in <i>Ixodes scapularis</i> ticks","year":2024,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; University of Saskatchewan","keywords":"Ixodes scapularis; Borrelia burgdorferi; Biology; Tick; Lyme disease; Spirochaetaceae; Ixodidae; Ixodes; Borrelia; Nymph; Borrelia Burgdorferi Infection; Virology; Microbiology; Immunology; Antibody; Zoology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001520777,0.0003513587,0.0002234144,0.000317402,0.0001755176,0.0003615861,0.0001653884,0.0003620457,0.001240773],"category_scores_gemma":[0.0001835333,0.0001973955,0.0003552526,0.00008781354,0.0003393455,0.0001701005,0.0002309899,0.0006624101,0.0003405163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003048149,"about_ca_system_score_gemma":0.000149763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00124337,"about_ca_topic_score_gemma":0.002143952,"domain_scores_codex":[0.999778,0.00003446464,0.00001549738,0.00005707492,0.00002773049,0.00008721706],"domain_scores_gemma":[0.9997839,0.00001168094,0.00007870438,0.00001655134,0.00002113411,0.0000880692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007271632,0.0001500705,0.009027866,0.00005158983,0.00002742006,0.0000716146,0.00004621097,0.0000740394,0.9880563,0.00004352717,0.0001897667,0.00153435],"study_design_scores_gemma":[0.0001323744,0.003456657,0.8053192,0.00005158713,0.0001873298,0.0008257767,0.0004846289,0.001971602,0.1833201,0.000135097,0.004076631,0.00003906789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988689,0.0003328832,0.0001134661,0.00006617336,0.00001477778,0.000007557965,0.0002202455,0.00001882742,0.0003570895],"genre_scores_gemma":[0.9978535,0.0002224897,0.0001804936,0.0001608032,0.00001569645,0.00002637621,0.0003498997,0.00001124815,0.001179411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00124337,"threshold_uncertainty_score":0.004150748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004098303259998597,"score_gpt":0.189545917374054,"score_spread":0.1854476141140554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}