{"id":"W4404133614","doi":"10.1002/cac2.12624","title":"FOXO1 or not FOXO1: that is the question","year":2024,"lang":"en","type":"article","venue":"Cancer Communications","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"Ligue Contre le Cancer; Bristol-Myers Squibb","keywords":"FOXO1; Cytotoxic T cell; Granzyme B; Biology; Cell biology; Transcription factor; Cancer research; Chemistry; In vitro; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002679829,0.0006174919,0.001875138,0.0005006279,0.000954522,0.00231782,0.001350206,0.003574576,0.008287341],"category_scores_gemma":[0.002644615,0.0003061307,0.0005690446,0.0007319786,0.005127948,0.005458195,0.001378719,0.004380731,0.003501182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001281387,"about_ca_system_score_gemma":0.001734727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001316675,"about_ca_topic_score_gemma":0.00145675,"domain_scores_codex":[0.999199,0.00009269181,0.00004950725,0.0003188155,0.0001341412,0.0002058206],"domain_scores_gemma":[0.998087,0.000533962,0.0002997956,0.0001416894,0.0004671316,0.0004703848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00230816,0.0003557431,0.01358234,0.008403336,0.0005317415,0.001269286,0.00150826,0.0006072582,0.03695625,0.1319931,0.3139635,0.488521],"study_design_scores_gemma":[0.0001667588,0.0005014111,0.009005895,0.002440513,0.0001985365,0.001668621,0.003022062,0.0005262808,0.005729649,0.1304111,0.8461887,0.0001404192],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.0262862,0.5476633,0.005752996,0.3879641,0.01550299,0.00003538141,0.002242405,0.000307498,0.01424512],"genre_scores_gemma":[0.2637004,0.5293312,0.003313212,0.1469246,0.02824364,0.0001297242,0.001791002,0.0002617363,0.02630446],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.008287341,"threshold_uncertainty_score":0.02772391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2035524097820991,"score_gpt":0.4773397007046023,"score_spread":0.2737872909225032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}