{"id":"W4404136743","doi":"10.1016/j.conctc.2024.101390","title":"Modeling severe uncontrolled asthma: Transitioning away from health states","year":2024,"lang":"en","type":"article","venue":"Contemporary Clinical Trials Communications","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SNC-Lavalin (Canada)","funders":"Regeneron Pharmaceuticals; Sanofi","keywords":"Asthma; Medicine; Environmental health; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006859785,0.0002563384,0.001594184,0.0001417556,0.000398935,0.0001370157,0.0004386536,0.0002068826,0.0001647362],"category_scores_gemma":[0.002177762,0.0001996107,0.001005903,0.0003011294,0.0002453767,0.0002607108,0.0001369829,0.0008394187,0.0001392198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006830709,"about_ca_system_score_gemma":0.002118464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002721436,"about_ca_topic_score_gemma":0.00005819152,"domain_scores_codex":[0.9917273,0.004205914,0.00302398,0.0004997363,0.0002869256,0.0002561715],"domain_scores_gemma":[0.9889026,0.008373667,0.0002872311,0.001733577,0.0001818476,0.0005210193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.008644908,0.006776128,0.01208045,0.001071781,0.006980822,0.000419357,0.004548721,0.004804424,0.0007345678,0.008720276,0.1141683,0.8310503],"study_design_scores_gemma":[0.01564052,0.001278632,0.001655932,0.003755818,0.000538975,0.00002349561,0.002881101,0.5885136,0.00001503999,0.007155035,0.3778508,0.0006910555],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1561044,0.5235267,0.1007377,0.1941795,0.002485938,0.006437532,0.002581229,0.002253606,0.01169345],"genre_scores_gemma":[0.9848576,0.004795842,0.002971657,0.004737428,0.0007723093,0.0001228116,0.001433585,0.00005447231,0.0002542803],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8303592,"threshold_uncertainty_score":0.8139888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3620200186460999,"score_gpt":0.5033473994838688,"score_spread":0.1413273808377689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}