{"id":"W4404142527","doi":"10.1002/gcc.70006","title":"Malignant Peripheral Nerve Sheath Tumor (<scp>MPNST</scp>) With Smooth Muscle Differentiation of the Uterus—A Case Report With Emphasis on Diagnostic Pitfalls and Value of <scp>DNA</scp> Methylation Analysis","year":2024,"lang":"en","type":"article","venue":"Genes Chromosomes and Cancer","topic":"Neurofibromatosis and Schwannoma Cases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Health and Medical Research Fund","keywords":"Biology; Malignant peripheral nerve sheath tumor; DNA methylation; Uterus; Cell biology; Methylation; Cancer research; Pathology; Endocrinology; DNA; Immunohistochemistry; Immunology; Genetics; Gene; Medicine; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003119626,0.001630343,0.0007536185,0.001760902,0.001863785,0.001154176,0.0008297355,0.003117342,0.001158551],"category_scores_gemma":[0.001450332,0.001308317,0.0007569704,0.001094881,0.00165528,0.00164022,0.001470336,0.00137086,0.0007241854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007974451,"about_ca_system_score_gemma":0.0004393158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001553486,"about_ca_topic_score_gemma":0.001902486,"domain_scores_codex":[0.9995351,0.00006239189,0.00006737364,0.000127993,0.00007250962,0.0001346492],"domain_scores_gemma":[0.9992676,0.0001742205,0.0002092082,0.0001010289,0.00003582671,0.0002120988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0000269476,0.00002048084,0.007885487,0.00003819828,0.00001181622,0.9887284,0.0002041971,0.00005270366,0.001316279,0.0001010572,0.0001859227,0.001428496],"study_design_scores_gemma":[0.000006237963,0.00004449629,0.005532834,0.000008831013,0.00001606324,0.9930195,0.0001134384,0.0001838157,0.0005159382,0.00006301976,0.0004869776,0.000008858022],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881188,0.004738439,0.002358948,0.001116545,0.0001455678,0.0001110617,0.0001080766,0.0001115844,0.003190914],"genre_scores_gemma":[0.996025,0.001457884,0.001019725,0.0002473191,0.0004993064,0.00002211222,0.00005391331,0.000009478804,0.0006653987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003117342,"threshold_uncertainty_score":0.005785942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01139988459919232,"score_gpt":0.2504321070392005,"score_spread":0.2390322224400082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}