{"id":"W4404160788","doi":"10.1016/j.ab.2024.115714","title":"Development of an assay to quantify tranexamic acid levels in plasma","year":2024,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Blood transfusion and management","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Thrombosis and Atherosclerosis Research Institute","funders":"Canadian Hemophilia Society; McMaster University; Margaret M. and Albert B. Alkek Department of Medicine","keywords":"Tranexamic acid; Chromatography; Chemistry; Plasma; Medicine; Surgery; Blood loss","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003397772,0.001682393,0.001344866,0.001907293,0.0006379404,0.001656235,0.001187425,0.003204135,0.002409782],"category_scores_gemma":[0.00590258,0.001063585,0.001254206,0.001103206,0.0009921886,0.001183504,0.001327258,0.003159316,0.002458918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006677531,"about_ca_system_score_gemma":0.00110289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007331783,"about_ca_topic_score_gemma":0.001239347,"domain_scores_codex":[0.9919009,0.002035357,0.0005263774,0.001840883,0.003322355,0.000374132],"domain_scores_gemma":[0.9965329,0.001138306,0.0006767129,0.00031121,0.001156327,0.0001845404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002677831,0.0002731157,0.003715034,0.0006409531,0.000131973,0.0001413876,0.0002492205,0.0004479874,0.9662734,0.0005131689,0.0007764142,0.02656939],"study_design_scores_gemma":[0.00006561696,0.00120048,0.006716268,0.0001865399,0.0001847627,0.001165162,0.0001656604,0.007246147,0.9705165,0.0006458867,0.01180113,0.0001058884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.2735224,0.02681174,0.6704265,0.002291072,0.001879235,0.002864163,0.004228169,0.004674493,0.01330225],"genre_scores_gemma":[0.4735073,0.01182747,0.4866293,0.002454458,0.0005555183,0.004695913,0.004552664,0.0002972802,0.01548001],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003397772,"threshold_uncertainty_score":0.01796937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03830025117630895,"score_gpt":0.3287735295742361,"score_spread":0.2904732783979271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}