{"id":"W4404168226","doi":"10.26434/chemrxiv-2024-6864j","title":"Unlocking the Aromatic Cope Rearrangement with Gold(I) Catalysis","year":2024,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Catalytic Alkyne Reactions","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Ministère de l'Éducation et de l'Enseignement supérieur; Agence Nationale de la Recherche","keywords":"Catalysis; Cope rearrangement; Chemistry; Stereochemistry; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009283725,0.0002991149,0.0001458413,0.00008215362,0.0000983826,0.0001848122,0.0001873269,0.0002222565,0.0007077425],"category_scores_gemma":[0.0001325837,0.0001077968,0.0001601455,0.00007650427,0.0002127729,0.0002313913,0.0004253103,0.0003358886,0.0002192356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002078347,"about_ca_system_score_gemma":0.0001653315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004426569,"about_ca_topic_score_gemma":0.0008712652,"domain_scores_codex":[0.9999034,0.000006643507,0.00000542218,0.00002311345,0.00002283931,0.00003849962],"domain_scores_gemma":[0.9999622,0.000006314682,0.00001074876,0.00000871353,0.000004682285,0.000007388655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004117687,0.0000243461,0.0001958907,0.00009114212,0.00001033884,0.0001456765,0.00006532191,0.000573581,0.9914439,0.001643038,0.0001552331,0.005610345],"study_design_scores_gemma":[0.0000122852,0.0001992905,0.0004962062,0.000004362138,0.000006209356,0.0001226289,0.00002000862,0.002127095,0.9943845,0.0001477404,0.002472431,0.000007238375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825691,0.0006212218,0.009279163,0.00008252656,0.00003537113,0.00003875493,0.00005365294,0.0001765281,0.007143727],"genre_scores_gemma":[0.9964945,0.0003211352,0.002173831,0.0000252636,0.000005746444,0.0000142038,0.00003365538,0.00001252097,0.0009192089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007077425,"threshold_uncertainty_score":0.002367616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01854204087940264,"score_gpt":0.2472382896963673,"score_spread":0.2286962488169647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}