{"id":"W4404171554","doi":"10.1021/acs.jproteome.4c00776","title":"The 2024 Report on the Human Proteome from the HUPO Human Proteome Project","year":2024,"lang":"en","type":"review","venue":"Journal of Proteome Research","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"NIH Clinical Center; National Center for Research Resources; National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Eye Institute; National Institute on Aging; National Institute of Diabetes and Digestive and Kidney Diseases; Biotechnology and Biological Sciences Research Council; Horizon 2020 Framework Programme; Knut och Alice Wallenbergs Stiftelse; European Commission; Staatssekretariat für Bildung, Forschung und Innovation; National Heart, Lung, and Blood Institute; Australian Government; National Institutes of Health; Directorate for Biological Sciences; European Molecular Biology Laboratory; National Human Genome Research Institute; Wellcome Trust; National Science Foundation","keywords":"Human proteome project; Proteome; Human proteins; Computational biology; Data science; Proteomics; Bioinformatics; Chemistry; Computer science; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","scholarly_communication","open_science","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0121035,0.0009495492,0.001715133,0.0004398334,0.003375491,0.001439237,0.005551517,0.000776251,0.0004789075],"category_scores_gemma":[0.001572432,0.0003904589,0.001591861,0.001757825,0.00107953,0.0001864684,0.00136837,0.01367574,0.000224185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001104788,"about_ca_system_score_gemma":0.002122191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001987605,"about_ca_topic_score_gemma":0.00002427782,"domain_scores_codex":[0.9903783,0.001002307,0.003011644,0.001092147,0.003224445,0.001291197],"domain_scores_gemma":[0.9907157,0.001869986,0.002539791,0.003532051,0.001104556,0.0002379552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003921352,0.001959573,0.00002376393,0.04926481,0.007634905,0.005281803,0.001520582,0.000004887424,0.05782254,0.0613522,0.461876,0.3528668],"study_design_scores_gemma":[0.0001474618,0.0002547165,9.985415e-7,0.01777122,0.000361758,0.0006877932,0.0001727854,0.000002732687,0.002908291,0.03428068,0.9429706,0.0004409065],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004589109,0.9605551,0.0001518668,0.007351454,0.000237009,0.0187543,0.0003310017,0.0001773187,0.011983],"genre_scores_gemma":[0.0001234719,0.9297022,0.001669846,0.00003392676,0.005224125,0.0220596,0.00008272322,0.0004029825,0.04070107],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4810947,"threshold_uncertainty_score":0.9998547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2469229862586829,"score_gpt":0.5217757164805483,"score_spread":0.2748527302218655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}