{"id":"W4404188426","doi":"10.1093/jpids/piae116","title":"Transition to Enteral Triazole Antifungal Therapy for Pediatric Invasive Candidiasis: Secondary Analysis of a Multicenter Cohort Study Conducted by the Pediatric Fungal Network","year":2024,"lang":"en","type":"article","venue":"Journal of the Pediatric Infectious Diseases Society","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Janssen Biotech; National Institute of Allergy and Infectious Diseases; Centers for Disease Control and Prevention; SymBio Pharmaceuticals Limited; Astellas Pharma; Pfizer; Melinta Therapeutics; Moderna; U.S. Department of Health and Human Services; Sanofi Pasteur; Seqirus; Amplyx; Gilead Sciences; Agency for Healthcare Research and Quality; Nabriva Therapeutics; National Institute of Diabetes and Digestive and Kidney Diseases; Sanofi; Allergan; AstraZeneca; Cystic Fibrosis Foundation; Eli Lilly and Company; Bristol-Myers Squibb; GlaxoSmithKline; National Institutes of Health; Shionogi","keywords":"Medicine; Invasive candidiasis; Antifungal; Voriconazole; Micafungin; Echinocandins; Caspofungin; Cohort; Tertiary care; Multicenter study; Intensive care medicine; Fluconazole; Internal medicine; Randomized controlled trial; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001455733,0.0004533451,0.0005102922,0.0004533931,0.0003941033,0.0006672289,0.0004794759,0.000338884,0.000981172],"category_scores_gemma":[0.00327356,0.0003493863,0.0007856195,0.0008537601,0.0002462979,0.0005042059,0.000565849,0.0007958948,0.0001367099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005654745,"about_ca_system_score_gemma":0.0008206298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007552311,"about_ca_topic_score_gemma":0.008522348,"domain_scores_codex":[0.9985594,0.000493532,0.0001239401,0.0003566731,0.0002405799,0.0002259255],"domain_scores_gemma":[0.9978364,0.0003533159,0.001059234,0.0002879045,0.0002392664,0.0002239061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007043452,0.0001490451,0.9975514,0.00001264364,0.0001317088,0.00007277203,0.0001098526,0.00003207671,0.0003223527,0.00001072259,0.0001225357,0.0007805877],"study_design_scores_gemma":[0.00008136765,0.0005769673,0.9983075,0.000007740411,0.00006978166,0.0002038161,0.0002335533,0.0001649834,0.0002192445,0.000005312231,0.0001258828,0.00000385187],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994172,0.00003791471,0.00004769177,0.000008090211,0.000002214415,0.00001814759,0.0004102802,0.000001355598,0.00005706983],"genre_scores_gemma":[0.9990799,0.00004491894,0.00008454267,0.00001906881,0.000004613287,0.00003146032,0.0006807235,0.0000025309,0.00005214104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007552311,"threshold_uncertainty_score":0.01501673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009569440582501454,"score_gpt":0.2775622645765839,"score_spread":0.2679928239940824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}