{"id":"W4404227324","doi":"10.1158/2159-8290.cd-24-0263","title":"Survivin Promotes Stem Cell Competence for Skin Cancer Initiation","year":2024,"lang":"en","type":"article","venue":"Cancer Discovery","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"HORIZON EUROPE Widening Participation and Strengthening the European Research Area; European Research Council; Stichting Tegen Kanker; Fonds De La Recherche Scientifique - FNRS; Fundação para a Ciência e a Tecnologia; Fonds Erasme","keywords":"Survivin; Stem cell; Cancer research; Cell biology; Biology; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001886067,0.0001884942,0.0002306794,0.00009226235,0.0001626794,0.0001081238,0.0001864397,0.000147973,0.0004272536],"category_scores_gemma":[0.000007369086,0.0001581286,0.0001481056,0.0001592909,0.0001240598,0.0004599447,0.00003558968,0.0001795305,0.00009195459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001289766,"about_ca_system_score_gemma":0.0004120704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003787754,"about_ca_topic_score_gemma":0.00008749971,"domain_scores_codex":[0.9989371,0.000128776,0.000240958,0.000326801,0.00003366521,0.0003327355],"domain_scores_gemma":[0.9993331,0.000335256,0.00006807438,0.0002009756,0.00005278567,0.000009840526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006615085,0.00008508709,0.0008263054,0.0004041372,0.0003288561,0.000002068345,0.001599766,0.00004165024,0.9352503,0.001196852,0.007158068,0.05244539],"study_design_scores_gemma":[0.0007883907,0.0001622054,0.002626386,0.0003919764,0.00007441545,0.000006506041,0.0002938991,0.00004384778,0.8152623,0.0001401222,0.1799162,0.0002938269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7733108,0.2178991,0.002191696,0.0004736574,0.004394732,0.000568303,0.0006648725,0.0001284455,0.0003684192],"genre_scores_gemma":[0.9706525,0.00418706,0.00001533825,0.0002319469,0.0001189568,0.000597045,0.0001041444,0.00003792559,0.0240551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.213712,"threshold_uncertainty_score":0.6448299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02020729623360466,"score_gpt":0.2767547806220824,"score_spread":0.2565474843884777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}