{"id":"W4404230728","doi":"10.1093/neuonc/noae165.0955","title":"EXTH-24. THERAPEUTIC TARGETING OF MISLOCALIZED NUCLEAR ENVELOPE PROTEINS IN<i>MYC</i>-DRIVEN GROUP 3 MEDULLOBLASTOMA","year":2024,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; National Research Council Canada; University of Toronto; McMaster University; Hamilton Health Sciences","funders":"","keywords":"Medulloblastoma; Envelope (radar); Group (periodic table); Cancer research; Neuroscience; Biology; Chemistry; Computer science; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001118038,0.0002242386,0.0003063882,0.0001912301,0.0001239831,0.0003085831,0.0002011597,0.0002919615,0.00205708],"category_scores_gemma":[0.00006439166,0.00009547189,0.0002836502,0.0001422069,0.0001894594,0.0001144523,0.0001221432,0.0007310135,0.0005978348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003446576,"about_ca_system_score_gemma":0.0002682597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007963216,"about_ca_topic_score_gemma":0.001534799,"domain_scores_codex":[0.9999169,0.000007702636,0.000004687764,0.00001878387,0.00002699141,0.000025005],"domain_scores_gemma":[0.999963,0.000004419181,0.000009648687,0.000004695471,0.00000341977,0.00001471357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008383346,0.0002844266,0.0003130758,0.0001134387,0.00002582045,0.0001652983,0.00002931225,0.0004558022,0.9898636,0.0002356473,0.0007062688,0.006969017],"study_design_scores_gemma":[0.0001920896,0.00237864,0.005133394,0.00001409826,0.00005502417,0.0004779046,0.00004718488,0.002354671,0.9765885,0.0001099366,0.01263564,0.0000128793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907404,0.001629555,0.001728169,0.0001627251,0.0001097378,0.0001412397,0.002703398,0.0003665129,0.00241835],"genre_scores_gemma":[0.9904784,0.000773561,0.001495607,0.0001087254,0.000009200274,0.0001101713,0.002609477,0.00004850445,0.004366368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00205708,"threshold_uncertainty_score":0.006881595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00980264798282271,"score_gpt":0.2538272993630138,"score_spread":0.2440246513801911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}