{"id":"W4404237582","doi":"10.1093/neuonc/noae165.0033","title":"EPCO-34. DECIPHERING THE LONGITUDINAL TRAJECTORIES OF GLIOBLASTOMA BY INTEGRATIVE SINGLE-CELL GENOMICS","year":2024,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Glioblastoma; Biology; Computational biology; Neuroscience; Evolutionary biology; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005620423,0.0002283303,0.0004915824,0.0005218464,0.0002794269,0.000673713,0.0002250843,0.0002605061,0.001301722],"category_scores_gemma":[0.0005924171,0.0001800023,0.0003541452,0.0006580167,0.0002343643,0.0002412988,0.0004058403,0.0003874497,0.000730715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003583847,"about_ca_system_score_gemma":0.0004888659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002324932,"about_ca_topic_score_gemma":0.005320676,"domain_scores_codex":[0.9998032,0.00002461834,0.00001118731,0.00007887437,0.00004277967,0.00003926907],"domain_scores_gemma":[0.9997476,0.00006273502,0.00004785997,0.00004286226,0.00006498858,0.00003395331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000430628,0.00005279112,0.0788808,0.0002530796,0.000134009,0.0001827086,0.0002821931,0.004811947,0.8763672,0.001241395,0.001792609,0.03557058],"study_design_scores_gemma":[0.0000392697,0.0003865117,0.6409409,0.00006823378,0.0002385524,0.0008635162,0.0005009609,0.05079154,0.2763574,0.003369924,0.02635743,0.00008567579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9415667,0.0009054512,0.03467502,0.0001984333,0.00003480904,0.00007098951,0.02026779,0.0005330843,0.001747646],"genre_scores_gemma":[0.9541116,0.0004458844,0.02240309,0.0001366298,0.00001868454,0.0001781405,0.02116618,0.0002466521,0.001293223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002324932,"threshold_uncertainty_score":0.004622817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01606178474327633,"score_gpt":0.2519497478516496,"score_spread":0.2358879631083733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}